Increlex (mecasermin) Disease Interactions
There are 4 disease interactions with Increlex (mecasermin):
Mecasermin (applies to Increlex) diabetics
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus
Mecasermin has insulin-like hypoglycemic effects, therefore, care should be taken when prescribing this agent to diabetic patients. It is recommended to monitor blood glucose levels in these patients until a well-tolerated dose is established and subsequently as medically indicated.
Mecasermin (applies to Increlex) lymphoid tissue hypertrophy
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Sleep Apnea
Lymphoid tissue (e.g., tonsillar and adenoidal) hypertrophy associated with complications such as snoring, sleep apnea, and chronic middle-ear effusions have been reported with the use of mecasermin. Patients presenting these complications should be periodically examined to rule-out the occurrence of lymphoid tissue hypertrophy. Care should be taken when prescribing mecasermin to these patients.
Mecasermin (applies to Increlex) scoliosis
Moderate Potential Hazard, Moderate plausibility.
Because mecasermin increases growth rate, patients who experience rapid growth should be closely monitored for any onset of a limp or complaints of hip or knee pain. Patients with a history of scoliosis who are treated with mecasermin should be monitored for progression of scoliosis. Care should be taken when prescribing this agent to patients with a history of scoliosis.
Mecasermin (applies to Increlex) visual complications
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance
Intracranial hypertension with papilledema, visual changes, headache, nausea and/or vomiting have occurred in patients treated with mecasermin. Ophthalmologic examination is recommended at the initiation and periodically during the course of mecasermin therapy. Assessment is recommended prior to prescribing this agent to patients with ocular complications.
Increlex (mecasermin) drug interactions
There are 24 drug interactions with Increlex (mecasermin)
More about Increlex (mecasermin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: insulin-like growth factors
- FDA Approval History
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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