MenHibrix Disease Interactions
There are 3 disease interactions with MenHibrix (haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine).
Meningococcal conjugate vaccine (applies to MenHibrix) GBS
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Guillain-Barre Syndrome
Persons previously diagnosed with Guillain-Barre syndrome (GBS) may be at increased risk of GBS following receipt of meningococcal conjugate vaccine. The decision to give this vaccine should take into account the potential benefits and risks.
References (2)
- (2024) "Product Information. Penbraya (cvx 316) (meningococcal group ACWY conjugate-group B vaccine (cvx 316))." Pfizer U.S. Pharmaceuticals Group
- (2025) "Product Information. Penmenvy (cvx 328) (meningococcal group ACWY conjugate-group B vaccine (cvx 328))." GlaxoSmithKline
Vaccines (applies to MenHibrix) IM injection
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Thrombocytopathy, Coagulation Defect, Thrombocytopenia, Thrombocytopathy, Coagulation Defect
In patients with thrombocytopenia or coagulation disorders, IM injections may produce bleeding and hematomas. Patients with a platelet count less than 50,000/mm3 are at an increased risk. Caution is advised if the vaccine (e.g., plague vaccine; hepatitis A and B vaccines; aluminum-adsorbed DTaP, DTP, DT, or Td) must be administered IM. The risk of bleeding may be minimized by vaccination immediately after the administration of replacement factor, use of a 23-gauge (or smaller) needle, and immediate application of direct pressure to the vaccination site for at least 2 minutes.
References (10)
- (2001) "Product Information. Plague Vaccine (plague vaccine)." Greer Laboratories Inc
- "Product Information. Cholera Vaccine (cholera vaccine)." Wyeth-Ayerst Laboratories
- "Product Information. Havrix (HepA) (hepatitis A adult vaccine)." SmithKline Beecham
- (2022) "Product Information. Engerix-B (HepB) (hepatitis B adult vaccine)." Apothecon Inc
- (2005) "Product Information. Menactra (meningococcal conjugate vaccine)." sanofi pasteur
- (2022) "Product Information. ActHIB (Hib) (haemophilus b conjugate (PRP-T) vaccine)." sanofi pasteur
- (2010) "Product Information. Imogam Rabies-HT (rabies immune globulin, human)." sanofi pasteur
- (2015) "Product Information. Hyperrab S/D (rabies immune globulin, human)." Grifols Therapeutics
- (2022) "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc
- (2024) "Product Information. Mresvia Prefilled Syringe (cvx 326) (RSV mRNA vaccine (cvx 326))." Moderna US, Inc
Vaccines (live attenuated/toxoid) (applies to MenHibrix) immunocompromised
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Immunodeficiency, Immunodeficiency
The expected antibody responses may not be obtained when live attenuated vaccines and/or toxoids are administered to immunosuppressed persons, including those receiving immunosuppressive therapy. Caution and close monitoring is advised.
References (9)
- (2005) "Product Information. Menactra (meningococcal conjugate vaccine)." sanofi pasteur
- (2022) "Product Information. ActHIB (Hib) (haemophilus b conjugate (PRP-T) vaccine)." sanofi pasteur
- (2022) "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc
- (2022) "Product Information. Trumenba (meningococcal group B vaccine)." Pfizer U.S. Pharmaceuticals Group
- (2022) "Product Information. Hiberix (Hib) (haemophilus b conjugate (PRP-T) vaccine)." GlaxoSmithKline
- (2016) "Product Information. Vaxchora (cholera vaccine, live)." PaxVax
- (2022) "Product Information. Vaxchora (cholera vaccine, live)." Emergent Travel Health, Inc
- (2023) "Product Information. Ixchiq (cvx 317) (chikungunya vaccine, live (cvx 317))." Valneva USA
- (2025) "Product Information. Penmenvy (cvx 328) (meningococcal group ACWY conjugate-group B vaccine (cvx 328))." GlaxoSmithKline
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MenHibrix drug interactions
There are 301 drug interactions with MenHibrix (haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine).
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More about MenHibrix (haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine)
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- FDA approval history
- Drug class: bacterial vaccines
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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