NovoSeven RT (coagulation factor viia) Disease Interactions
There are 2 disease interactions with NovoSeven RT (coagulation factor viia):
Coagulation factor VIIa (applies to NovoSeven RT) thrombosis
Major Potential Hazard, Moderate plausibility. Applicable conditions: Thrombotic/Thromboembolic Disorder, Liver Disease, Heart Disease
Serious arterial and venous thrombotic events have been reported with the use of coagulation factor VIIa. Patients at an increased risk of thromboembolic complications may include those with a history of coronary heart disease, liver disease, disseminated intravascular coagulation, post-operative immobilizations, elderly patients, and neonates. It is recommended to exercise caution when administering coagulation factor VIIa to patients at risk and the potential benefit of treatment should be weighed against the risk of these complications.
Coagulation factor VIIa (applies to NovoSeven RT) allergies
Moderate Potential Hazard, Moderate plausibility.
Hypersensitivity reactions, including anaphylaxis, can occur with coagulation factor VIIa. Patients with a known hypersensitivity to mouse, hamster, or bovine proteins may be at a higher risk of hypersensitivity reactions. Discontinue infusion and administer appropriate treatment when hypersensitivity reactions occur.
NovoSeven RT (coagulation factor viia) drug interactions
There are 5 drug interactions with NovoSeven RT (coagulation factor viia)
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- Drug class: miscellaneous coagulation modifiers
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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