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Betibeglogene autotemcel Disease Interactions

There are 3 disease interactions with betibeglogene autotemcel.

Moderate

Betibeglogene (applies to betibeglogene autotemcel) HIV

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: HIV Infection

Betibeglogene has not been studied in patients with HIV. A negative serology test for HIV is necessary before the collection of cells, to ensure acceptance of apheresis material for betibeglogene manufacturing. Material from patients with a positive HIV test, will not be accepted for manufacturing.

Moderate

Betibeglogene (applies to betibeglogene autotemcel) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Betibeglogene has not been studied in patients with hepatic impairment. Patients should be assessed for hepatic impairment to ensure that hematopoietic stem cell (HSC) transplantation is appropriate. Additionally, screening for hepatitis B and C should be performed before cell collection, to ensure acceptance of apheresis material for betibeglogene manufacturing.

Moderate

Betibeglogene (applies to betibeglogene autotemcel) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Betibeglogene has not been studied in patients with renal impairment. Patients should be assessed for renal impairment, to ensure that hematopoietic stem cell (HSC) transplantation is appropriate.

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Betibeglogene autotemcel drug interactions

There are 44 drug interactions with betibeglogene autotemcel.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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