Definition: A chelating agent, developed as an antidote for lewisite and other arsenical poisons. It acts by competing for the metal with the essential —SH groups in the pyruvate oxidase system of the cells and forms, with arsenic, a stable, relatively nontoxic cyclic compound, the metal having a greater affinity for it than for the —SH groups of the cell proteins; also used as an antidote for antimony, bismuth, chromium, mercury, gold, and nickel.
Synonym(s): antilewisite, British anti-Lewisite
Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.