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Sotradecol (Intravenous)

Generic Name: sodium tetradecyl sulfate (Intravenous route)

SOE-dee-um tet-ra-DEK-ul SUL-fate

Medically reviewed on June 7, 2018

Commonly used brand name(s)

In the U.S.

  • Sotradecol

Available Dosage Forms:

  • Solution

Therapeutic Class: Sclerosing Agent

Uses For Sotradecol

Sodium tetradecyl sulfate injection is used to treat small varicose veins of the lower legs. It is a type of medicine called a sclerosing agent.

This medicine is to be given only by or under the direct supervision of your doctor.

Before Using Sotradecol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of sodium tetradecyl sulfate injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of sodium tetradecyl sulfate injection in geriatric patients.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Asthma or
  • Blood clotting problems (eg, phlebitis migrans, thrombophlebitis) or
  • Blood problems (eg, dyscrasia, sepsis) or
  • Blood vessel problems (eg, deep vein incompetence, huge superficial veins with connections to deeper veins, valvular vein incompetence) or
  • Cancer or
  • Cellulitis, acute or
  • Diabetes, uncontrolled or
  • Hyperthyroidism (overactive thyroid) or
  • Infection, acute or
  • Lung disease, acute or
  • Prolonged immobilization (eg, bedridden) or
  • Skin disease, acute or
  • Tuberculosis or
  • Varicosities caused by abdominal and pelvic tumors (unless the tumor has been removed)—Should not be used in patients with these conditions.
  • Blood vessel disease (eg, peripheral arteriosclerosis, thromboangiitis obliterans or Buerger's disease)—Use with caution. May make these conditions worse.

Proper Use of Sotradecol

A nurse or other trained health professional will give you this medicine in a medical facility. It is injected into the veins of your legs.

Precautions While Using Sotradecol

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor or nurse right away if you have a rash, itching, hoarseness, trouble with breathing or swallowing, or any swelling of your hands, face, or mouth after receiving this medicine.

This medicine may increase your risk of having blood clots in the brain, heart, blood vessels, or lungs, which may lead to stroke, heart attack, deep vein thrombosis, or pulmonary embolism. Check with your doctor right away if you have difficulty with speaking, slow speech, inability to speak, inability to move the arms, legs, or facial muscles, chest pain or discomfort, pain or discomfort in the arms, jaw, back, or neck, pain, redness, or swelling in the arm or leg, troubled breathing, or dizziness or lightheadedness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Sotradecol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

  • Anxiety
  • blue-green to black skin discoloration
  • blurred vision
  • chest pain or discomfort
  • cough
  • difficulty breathing or swallowing
  • dizziness or lightheadedness
  • fainting
  • fast heartbeat
  • hives, itching, skin rash
  • inability to speak
  • nausea
  • noisy breathing
  • pain or discomfort in the arms, jaw, back, or neck
  • pain, itching, redness, peeling, or cracking of the skin at the injection site
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • raised red swellings on the skin, lips, tongue, or in the throat
  • seizures
  • severe or sudden headache
  • slurred speech
  • temporary blindness
  • tightness in the chest
  • unusual tiredness or weakness
  • vomiting
  • weakness in the arm or leg on one side of the body, sudden and severe

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Headache
  • permanent discoloration of the injected vein
  • red, itchy, or watery eyes
  • runny or stuffy nose
  • sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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