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Ocusert Pilo (Ophthalmic)

Generic name: pilocarpine [ pye-loe-KAR-peen ]
Brand names: Isopto Carpine, Ocu-Carpine, Ocusert Pilo, Pilocar, Pilopine-HS, Qlosi
Drug class: Ophthalmic glaucoma agents

Medically reviewed by Last updated on Jun 14, 2024.

Uses for Ocusert Pilo

Pilocarpine is used to treat glaucoma and other eye conditions. Vuity® eye drops and Qlosi™ eye drops are used to treat presbyopia (age-related eye or vision problem).

This medicine is available only with your doctor's prescription.

Before using Ocusert Pilo

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Vuity® eye drops and Qlosi™ eye drops are not indicated for use in children.


Appropriate studies on the relationship of age to the effects of pilocarpine eye drops have not been performed in the geriatric population. However, geriatric-specific problems that would limit the usefulness of this medicine in the elderly are not expected.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Proper use of Ocusert Pilo

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects.

To use the eye drops:

To use the eye gel:

To use the eye insert:

If you wear contact lenses, take them out before you use this medicine. Wait at least 10 minutes before you put your contact lenses back in.

If you are using more than one eye product, apply these medicines at least 5 minutes apart.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the Qlosi™ vial in the refrigerator. Once the pouch is open, you may store it at room temperature and use within 30 days. Throw away opened vials after use.

Precautions while using Ocusert Pilo

If you will be using this medicine for more than a few weeks, your eye doctor will check your eyes at regular visits to make sure it is working properly and is not causing unwanted effects.

Serious eye or vision problems (eg, retinal detachment, retinal tear) may occur during treatment with this medicine. Check with your doctor right away if you are seeing flashes or sparks of light, seeing floating spots before the eyes, or a veil or curtain appearing across part of your vision.

For patients using the eye drops or eye gel:

For patients using the eye insert:

Side Effects of Ocusert Pilo

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Less common

Incidence not known

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Commonly used brand name(s)

In the U.S.

In Canada

Available Dosage Forms:

Therapeutic Class: Direct Acting Miotic

Pharmacologic Class: Cholinergic System

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.