Medically reviewed by Drugs.com. Last updated on Feb 3, 2022.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Hemostatic
Uses for fibrinogen
Fibrinogen injection is used to treat acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
Fibrinogen is to be given only by or under the supervision of a doctor.
Before using fibrinogen
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fibrinogen, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to fibrinogen or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fibrinogen injection in children.
Appropriate studies on the relationship of age to the effects of fibrinogen injection have not been performed in the geriatric population. However, no geriatric-specific problems have been documented to date.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper use of fibrinogen
A doctor or other trained health professional will give you fibrinogen. Fibrinogen is given through a needle placed in one of your veins.
Precautions while using fibrinogen
It is very important that your doctor check you closely while you are receiving fibrinogen to make sure it is working properly. Blood tests will be needed to check for unwanted effects.
Fibrinogen may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching skin, difficulty with swallowing, dizziness, a fast heartbeat, lightheadedness or fainting, restlessness, trouble breathing, swelling in your face, hands, tongue, or throat, or chest pain after you receive the medicine.
Fibrinogen may increase your chance of having blood clotting problems. Tell your doctor right away if you have a sudden or severe headache, problems with vision or speech, chest pain, or numbness or weakness while you are receiving fibrinogen.
Fibrinogen is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them, although the risk is low. Human donors and donated blood are both tested for viruses to keep the transmission risk low. Talk with your doctor about this risk if you are concerned.
Fibrinogen side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Chest pain
- dizziness or lightheadedness
- numbness or tingling in the hands or feet
- unusual tiredness or weakness
Incidence not known
- chest discomfort or tightness
- difficult or labored breathing
- difficulty with swallowing
- fast heartbeat
- pain or discomfort in the arms, jaw, back, or neck
- pain, redness, or swelling in the arm or leg
- pains in the groin or legs, especially in the calves of the legs
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- severe headaches of sudden onset
- skin rash, hives, or itching
- sudden loss of coordination
- sudden onset of slurred speech
- sudden vision changes
- trouble breathing
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
More about fibrinogen
- Side effects
- Drug interactions
- Dosage information
- During pregnancy
- En español
- Drug class: miscellaneous coagulation modifiers
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.