Comparing Rebif vs Tecfidera
| Rebif (interferon beta-1a) | Tecfidera (dimethyl fumarate) |
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| Rebif (interferon beta-1a) | Tecfidera (dimethyl fumarate) |
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Prescription only
Rebif may be used to reduce the frequency of exacerbations of MS and delay the progression of the disease in adults. It is usually self-administered by SC injection three times per week and the most... View more |
Prescription only
Tecfidera is a disease-modifying drug that may be used to reduce disease progression and relapses in people with multiple sclerosis. Flushing and gastrointestinal effects are the most common initial... View more |
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| More about Rebif (interferon beta-1a) | More about Tecfidera (dimethyl fumarate) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Rebif has an average rating of 6.8 out of 10 from a total of 29 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Tecfidera has an average rating of 6.2 out of 10 from a total of 101 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Rebif side effects |
View all Tecfidera side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rebif prices |
View all Tecfidera prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other interferon beta-1a brands include: Avonex, Avonex Pen, Avonex Prefilled Syringe, Rebif Rebidose |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 342 drugs are known to interact with Rebif:
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A total of 639 drugs are known to interact with Tecfidera:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 07, 2002 |
March 27, 2013 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.