Comparing Lybalvi vs Saphris
| Lybalvi (olanzapine / samidorphan) | Saphris (asenapine) |
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| Lybalvi (olanzapine / samidorphan) | Saphris (asenapine) |
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Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Saphris may also be used for purposes not listed in this medication guide. |
Related suggestions Schizophrenia
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| More about Lybalvi (olanzapine / samidorphan) | More about Saphris (asenapine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lybalvi has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 6% reported a negative effect. |
Saphris has an average rating of 7.4 out of 10 from a total of 318 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Lybalvi side effects |
View all Saphris side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lybalvi prices |
View all Saphris prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other asenapine brands include: Secuado | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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54 hours (empirically) |
24 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 702 drugs are known to interact with Lybalvi:
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A total of 653 drugs are known to interact with Saphris:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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May 28, 2021 |
August 13, 2009 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.