Comparing Cinryze vs Firazyr

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Cinryze C1 esterase inhibitor (human)

Firazyr icatibant

Cinryze works by replacing missing C1 protein in the blood in adults and children over the age of 6 with hereditary angioedema (HAE) preventing the generation of bradykinin and angioedema attacks... View more

Prescribed for Hereditary Angioedema. Firazyr may also be used for purposes not listed in this medication guide.

Prescription only

Ratings & Reviews

View all 4 reviews

View all 5 reviews

Drug Class

Hereditary angioedema agents

Hereditary angioedema agents

Side Effects

Common side effects include: headache.

See the full Cinryze side effects document.

Common side effects include: hematoma at injection site, injection site reaction, urticaria at injection site, bruising at injection site, burning sensation at injection site, erythema at injection site, irritation at injection site, pain at injection site, and swelling at injection site.

See the full Firazyr side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	1 powder for injection
Dosage	500 units
Per Unit^*	$2,976.08
Cost^*	$2,976.08

View all Cinryze prices

Quantity	3 mL
Dosage	10 mg/mL
Per Unit^*	$3,882.49
Cost^*	$11,647.48

View all Firazyr prices and generic prices

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Generic Availability

Yes

Dosage Form(s) Available

Intravenous powder for injection

Subcutaneous solution

Brand Names

Other C1 esterase inhibitor (human) brands include: Berinert, Haegarda

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

152 hours

1.8 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 44 drugs are known to interact with Cinryze:

4 major drug interactions (8 brand and generic names)
39 moderate drug interactions (244 brand and generic names)
1 minor drug interactions (3 brand and generic names)

A total of 11 drugs are known to interact with Firazyr:

11 moderate drug interactions (24 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

Thromboembolic events

No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

First Approval Date

N/A

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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