Comparing Cinryze vs Firazyr
| Cinryze | Firazyr |
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| Cinryze (C1 esterase inhibitor (human)) | Firazyr (icatibant) |
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Prescription only
Cinryze works by replacing missing C1 protein in the blood in adults and children over the age of 6 with hereditary angioedema (HAE) preventing the generation of bradykinin and angioedema attacks... View more |
Prescription only
Firazyr is used to treat attacks of hereditary angioedema (HAE) in adults (not children) and people can be taught how to self-administer it subcutaneously at home. Injection site reactions, such as... View more |
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| More about Cinryze (C1 esterase inhibitor (human)) | More about Firazyr (icatibant) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Cinryze has an average rating of 8.3 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 25% reported a negative effect. |
Firazyr has an average rating of 7.5 out of 10 from a total of 6 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Cinryze side effects in more detail. |
Common side effects include:
See also: Firazyr side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cinryze prices |
View all Firazyr prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other C1 esterase inhibitor (human) brands include: Berinert, Haegarda |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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152 hours |
1.8 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 44 drugs are known to interact with Cinryze:
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A total of 11 drugs are known to interact with Firazyr:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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N/A |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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N/A |
N/A |
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.