Carbidopa / levodopa and Tremors: What Users Say

• Mis...
• September 18, 2015

For Parkinson's Disease "I am a 63-year-old female and have had Parkinson's for 3 years. Sinemet worked well for me, but I was beginning to have downtime between doses. My neurologist started me on Rytary, and I took it for 2 months. Rytary gave me more energy and less downtime between doses but had horrible side effects. I tried adjusting my dosages, but no improvement. I was unable to sleep, had nausea and vomiting, lost significant weight, had chills, and my hands were shaky but sweat ran from my face. My temperature after the last dose of the day was 96.9. Then, I started having chest pains. I take Azilect, so that may have caused the Rytary to have a stronger effect. I was in bed most of the day. Switched back to Sinemet with doses every 3 hours and feel great!"

• The...
• March 2, 2021

For Parkinson's Disease "My father was diagnosed with Parkinson’s disease over 20 years ago (currently 71 years old). He has a DBS, suffers from dyskinesia, tremors, and gait. He’s been on 245 mg of Rytary 5 times a day for the past year. He’s had an unbelievably great response to Rytary (very little dyskinesia, minor tremors, and almost no gait issues for the past 12 months). This drug has changed his life, and I’m very thankful for it."

• mic...
• September 8, 2009

For Parkinson's Disease "I was placed on Sinemet CR (1 x 4 times daily) as a result of Sinemet 'wearing off.' I am a carer for my wife, who is extremely disabled, thus I needed a medication that allowed me to still manage her needs whilst controlling my Parkinson's. CR has worked, and although I have episodes of trembling as I get nearer the end of a 6-hour medication cycle, I am very happy with it as I am able to tend to my wife's medical needs and carry out cooking duties as required."

• Alm...
• February 17, 2020

For Parkinson's Disease "My 87-year-old dad has had Parkinson's disease since 2014. He’s been on 25/100 mg C/L, 2 pills 2 times a day. Then my dad’s left leg looked really weak like 3 weeks ago, and his neuro put him on Rytary 48.75 mg/195, 2 pills 3 times a day. The first dose he took at night (after his first 2 doses of C/L - morning and mid-afternoon), he was able to sleep all night and had more strength in his left leg. But 2 1/2 weeks later, he started hallucinating and seeing goats and people talking and hanging out the living room window. His stress level was up, and he had the worst shakes. He was restless and had little sleep. The neuro said to give him the dose with food, but my mom and my dad were exhausted from the hallucinations and little sleep. So we skipped his evening dose of Rytary, and he slept all night until late morning. We gave him C/L again and this time 2 pills 3 times a day. Still monitoring him to see how he does. I wonder if we can give him C/L and then one dose of Rytary in the evening??"

• Rob...
• Taken for 2 to 5 years
• December 16, 2021

For Parkinson's Disease "I have been on Sinemet 12.5/50 mg taken 4 times a day for 22 months, but now my tremor seems to be getting worse. I have now started taking 5 pills a day, but this only makes the tremors worse and my lower jaw tremors. Advise anyone?"