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Wellbutrin for Depression User Reviews

Wellbutrin has an average rating of 6.9 out of 10 from a total of 505 reviews for the treatment of Depression. 61% of reviewers reported a positive experience, while 22% reported a negative experience.

Wellbutrin rating summary

6.9/10 average rating

505 ratings from 544 user reviews.

Compare all 183 medications used in the treatment of Depression.

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Reviews for Wellbutrin

  • Court...
  • Taken for 1 to 6 months
  • April 23, 2021

"Background: depression, anxiety, intrusive thoughts, seasonal depression I went with Wellbutrin because it had the least side effects compared to most depression medications and it was recommended by many people. I must say it really has been life changing. When I started Wellbutrin it made me think much clearer. While I still do get thoughts, they are not intrusive. My mood is stable and I feel generally happy! Week 1- sensitivity to caffeine, racing heart for one day, increased energy, appetite decreased Week 2- energy balanced out, appetite low Week 3- appetite back, energy consistent, mood improving, felt happy and no intrusive thoughts Week 4- I feel great! I do sometimes experience ringing in my ear, but nothing that is bothersome. Overall, this medication has saved me. I recommend taking this medication while seeing your therapist. Both of them together have really pushed me in the right direction."

10 / 10
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716 Report
  • Kai
  • October 10, 2018

"I had an odd situation where I was not really depressed with sadness but I just felt nothing. I never got angry, never got happy- never wanted to do anything besides lay in bed. I tried to fake it as much as possible but I couldn’t anymore. I stopped answering my phone, lost all interest and motivation. I had taken all the antidepressants on the market but they made me feel crazy. My hands shook and I felt out of my body. I started researching the symptoms of low dopamine and I had almost all of the symptoms- poor memory, poor concentration, excessive worrying, lack of motivation- and overall just not giving a $#|+ about anything. I asked my doctor for Wellbutrin. In a couple of days I was calling old friends, kicking butt at work, and motivated for life again. My problem all along was dopamine not serotonin. I am thankful I figured it out. DON'T GIVE UP. Read about brain chemicals- dopamine, serotonin, and, norephenephrine- and make the choice based on research."

10 / 10
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1094 Report
  • Cance...
  • September 5, 2020

"I was a 250 pound fat and happy married man until I was diagnosed with stage 3B cancer. My wife and kids convinced me to see a Psych and get treated. Anyway, he started my on Wellbutrin (BUPROPION generic) at 200mg per day. He said this med has been around a long time and it's very safe and effective. Note that I don't have Anxiety. After a week on BUPROPION, I would sing on the way to work and was unable to take the smile off my face. After about 6 months these feelings wore off, but I was still better than before. My Psych upped the dosage to 300mg per day. I take two 100mg pills at 9am and then one 100mg pill at 230pm. Overall, I'm happy. It worked for me. Only side effects are a little insomnia twice per month and ringing in my ears 4 times per month, which lasts for hours each time. The ringing is very low. I get my meds Generic for a 90 day supply each time and my insurance charges me $24 for that 90 day supply (300mg/day)."

9 / 10
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481 Report

Frequently asked questions

  • TheTw...
  • Taken for less than 1 month
  • June 1, 2020

"I'm on day 3 of wellbutrin. So far it's been miserable. I'm on the lowest dose and still having horrible stomach side effects. I can't eat, I have no appetite, severe diarrhea with intense stomach pain. I'm also exhausted but can't seem to sleep more than a few hours at a time. My mouth is dry and my eyeballs feel like sandpaper. And to top it all off, just looking at my husband arouses me. I'd actually enjoy that side effect if I could stay off the toilet. I'm gonna try to stick it out in hopes that this will pass. I know I need to give it some time."

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474 Report
  • strug...
  • January 17, 2015

"I am a 35 year old woman, who has taken meds for 1/2 her life. I struggle with obsessive compulsive disorder, intrusive thoughts and overall depression. Wellbutrin.. I take 150mg a day. It has changed my life.. I have less obsessive thinking, more motivation and for some reason care way less about what people think."

9 / 10
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812 Report

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  • Anonymous
  • March 30, 2021

"Saved my life and marriage after I had severe PPD and PPA. I would still have some bad anxiety every once in a while but overall totally worth it. I also found that Benadryl really helps if you have anxiety with this at night. I was able to gain the confidence to start my own business and actually believe for the first time in my life I could truly accomplish something. I pray this med helps others like it’s helped me."

10 / 10
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344 Report
  • ZTano
  • March 12, 2014

"Five months after my Daughters fatal car accident, my Dr. suggested Celexa for my depression. I took it for 6 months. It made me worse, my Dr. thought that Wellbutrin might be better. It has really helped, just after 3 weeks I've noticed a big difference in my life. I take 200mg per day and now I can finally get on with my life knowing that some day we will be together."

9 / 10
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804 Report

More FAQ

  • rasin...
  • Taken for less than 1 month
  • May 27, 2020

"After a break up with my girlfriend and one true love of my life I went to a really dark place and had serious suicidal thoughts. I was first put on Brintellix, then Valdoxan and three weeks ago to Wellbutrin. It's been six months since the break up and after using this med for 3 weeks I'm finally able to enjoy life again and have energy to get through the days with pleasure. This med has so far been a life safer for me. First two weeks were hard and I had serious insomnia but now for the first time in 6 months I don't need Ambien to sleep anymore. I seriously recommend this med, at least for me its working perfectly so far. Just give it time to start working and you will feel better."

10 / 10
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392 Report
  • Pr23
  • December 23, 2019

"Okay, I came back to rate again. It has now been about a little over a month on Wellbutrin and wow it has saved my life. It was like a total switch in the way I think and feel everyday! For years and years I’ve been depressed but this year was so bad,I didn’t care about myself. I was also so unmotivated.. crying multiple times a day even while at work.. I’d be triggered by anything and start having anxiety attacks. Now, I can finally say I am happy with my life! It’s like I can see my life clearly now, it’s no longer a fog, I don’t obsess over all the negative things... I have energy to go to the gym often and eat right and I’ve lost over ten pounds. I have goals again and I have my self confidence back.I t feels unreal I did miss a few pills every other day for about a week and a half and I felt a difference, I cried once and I was also binge eating. But I went back to normal once I went back to taking all my pills on time."

10 / 10
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318 Report
  • Anonymous
  • October 25, 2014

"I am not a proponent of Big Pharma, and have always had to try to "deal" with my problems on my own. I have a really excellent diet, exercise, don't smoke, eat an organic diet - I'm just saying I really take care of myself. I have had anxiety (with a little bit of depression) all of my life. I was diagnosed with PTSD a few years ago, as I was having severe anxiety about being accepted into nursing school, and if I would be able to handle to stress and constant pressure, and I also have concentration problems. I have been off and on SSRIs, which have been nothing but terrible for me...Paxil, Zoloft, & Prozac, of which made me feel like a zombie. Wellbutrin is GOLD. Not tired, less irritable, not panicky. It has changed my life."

10 / 10
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538 Report
  • Natha...
  • June 6, 2021

"Just starting this med. The first couple days, I didn’t think it was doing much, but I noticed I couldn’t sleep for very long. I wasn’t as hopelessly sad as I had been the week prior, but I was experiencing an array of stomach-related side effects (constipated until I was very much no longer constipated, bloating, stomach aches, & VERY nauseous the first night). Fast forward a few days, I still can’t sleep very much. I’m artificially active is the best way to describe it. I’ve been pretty inactive throughout the pandemic, but I walked to get iced coffee in 90 degree heat, cleaned my apartment, had people over, then went to the gym later because I was so jittery and couldn’t sit still. It also has given me quite a bit of anxiety and some irritability alongside the constant need to be active. I hope that over the next few days, the anxious thoughts, stomach issues, & insomnia calm down."

8 / 10
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219 Report
  • jkn
  • January 1, 2015

"Before starting Wellbutrin I was so depressed, crying all the time, no motivation, no energy, no ability to make decisions or follow through with them, no desire to go anywhere. I've been taking Wellbutrin for about 3 weeks and within a 5 days I was noticing a difference. The crying has stopped, I'm more motivated, I have more energy and I'm making decisions I couldn't before. I have been active, forcing myself to go to the gym but now I'm more eager to go. Wellbutrin has made a huge difference for me."

9 / 10
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523 Report
  • Leigh
  • Taken for 1 to 6 months
  • January 2, 2021

"When I tried an SSRI I ended up lying on the floor almost unresponsive. I won't take one again. In the last year my depression and anxiety got really bad. Horrible panic attacks, slamming doors, screaming, irritability... then came the suicidal thoughts. My doctor suggested Wellbutrin. I have a very sensitive body so I started on 75 mg once a day. Man. I noticed a difference within the first day or two. The third day I woke up with tons of energy and unpacked my suitcase that had been sitting in my closet for a week, before I even started working! Unheard of for me. My outlook on life has improved, I don't snap at my husband, I don't get annoyed. Plus I've lost 4 lbs and my sex drive has increased slightly. The only side effects I've had were the brain "zingers" people talk about (they have subsided) and pretty bad insomnia. I'm hoping the insomnia goes away, but right now the positives definitely outweigh the negatives! A world of difference!"

9 / 10
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240 Report
  • KB80
  • October 6, 2014

"Well I am very pleased to tell you that I started Wellbutrin XL 150mg for depression and anxiety and I can honestly say that it is a miracle drug! I started feeling much better after just one day, I could not believe it. It has been 30 days now and I have not had even one side effect. My depression went away almost right away and the anxiety took a couple weeks. But 30 days later I feel completely myself again. This medication is definitely doing its job 100%."

10 / 10
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523 Report
  • Hannah
  • Taken for less than 1 month
  • December 8, 2019

"Best medication I’ve ever taken. I didn’t realize how depressed I was before taking it. Now I have energy to get through the day. It also helped with my obsessive thoughts. I’ve never felt so much relief in my life. The only side effect is a slightly dry mouth but I’d take that any day over the hell I was living in."

10 / 10
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270 Report
  • sad...
  • Taken for 1 to 6 months
  • January 22, 2019

"Wow. What an amazing drug. I have been on cymbalta for about 5 years, it was a life saver after a really bad period but began to lose its effectiveness. My doctor added wellbutrin 200mg and I feel like my old self again. Lots of energy, no feeling like the day is to hard to attack. No more feelings about giving up. No need for my daily nap. Wish I would have tried it 20 years ago could have saved a lot of needless pain. I am 40 now and have only been treated for depression for the last 5 years. If anyone out there feels sad all the time for no reason go to your doctor, it doesn't have to be that way. Anyway loving wellbutrin."

10 / 10
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292 Report
  • Woody
  • October 2, 2020

"I began Bupropion about a year ago. Took a while to kick in, Waiting eight weeks for the hoped-for effect was like waiting eight months. I had tried another med and it left me with negative sexual side effects which is why the doctor suggested Bupropion. I've been taking low dose Viagra, honestly don't know if I need it . . . but Viagra works. I told my doctor that I'm okay, but don't seem to feel any drastic change from when I first began the med. She suggested upping to 300 mg extended release. After a week I began to feel better but, don't know if it is from the med or the high of knowing I made the attempt at trying to feel better. Wishful thinking is a good way to put it. So here's my question: Since I was already taking Bupropion at 150 mg/day extended release should I expect the new dosage of 300 mg to take eight weeks to fully kick in? Has anyone had this experience?"

9 / 10
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216 Report
  • Sara
  • Taken for 1 to 6 months
  • February 17, 2017

"This has become my miracle medicine. Some days I wonder if it's too good to be true!! I've battled depression and anxiety on and off for years. My doctors over the years kept giving me different SSRIs and those made me like a zombie barely able to get out of bed. With a toddler that's just not an option! I've been on it for about 6 weeks now and let me tell you the benefits: I'm HAPPY - like I have a desire to move and do things as opposed to sitting on the couch after work not wanting to do a thing until bedtime. It's almost like I'm on speed. I'm SO productive at work and home. I'm sleeping better - I was worried it would keep me awake but nope. Sex drive thru the roof. I've lost 10 lbs so far from suppressed appetite and working out!"

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319 Report
  • It...
  • Taken for less than 1 month
  • November 25, 2014

"My wife passed away and I went into a deep depression. I was put on Wellbutrin and told by my nurse it would be at least 4 weeks. In just 3 days and I was feeling great, clear headed, I smiled, I ate normally."

10 / 10
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387 Report
  • depre...
  • Taken for 1 to 2 years
  • December 10, 2014

"I have been on bupropion for about a year, 150mg taken every morning. I noticed a difference on day 2. Everything was just normal. Not bad normal, but good normal, like you woke up after having a really good sleep - and like a weight or pressure has been lifted. It's really hard to describe. Everything seems better. I kid you not. Music sounds clearer, looking around outside, it looks clearer...like I am out of a fog. So...I tried an experiment while I went on vacation. Didn't take anything for 2 weeks. My mood slowly returned to negative. Little things ticked me off, that shouldn't have. I decided to go back on. Same effect on the next day, mood lifted. It gives me slight insomnia, but also takes away some appetite. Great."

10 / 10
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374 Report
  • new...
  • Taken for 1 to 6 months
  • November 20, 2013

"I was deeply depressed. I slept a lot, I lost interest in work (and I am self-employed). I suffered from chronic procrastination, lost many clients and went to trouble with my bank, an awful period. I tried SSRIs like sertraline and Lexapro but it didn't help me rise up and boost my motivation. Since I have discovered after 50 years that I am also suffering from ADD. I read about Wellbutrin. I tried 150 mg with no significant change for a month, and then, switch to 300 mg. What a change! I am full of energy, focused, full of self confidence, working full hours, and enjoy writing. "

10 / 10
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358 Report
  • ABano
  • Taken for 2 to 5 years
  • August 17, 2020

"I had Bipolar Disorder with depression and psychotic symptoms. I was put on Ability 15mg but I got Tardive Dyskinesia. The dosage was lowered to 10mg and then 5mg. I stopped with the psychotic symptoms immediately. But I was still depressed and not enjoying my life. So they added 150 mg Extended Release Wellbutrin and I got much better. I felt a little nauseous when I first started taking it but that stopped a few months into treatment. I still was requiring daily 1 to 2 hour naps to get through my day. Then my medicine was increased to Wellbutrin 150MG SR two times a day. Finally I felt like myself again. I had energy and felt like I could take on all my responsibilities again. It worked beautifully with Abilify for me. Hope it works for you!"

10 / 10
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156 Report
  • Justme
  • Taken for 1 to 6 months
  • August 4, 2018

"This medicine saved my life. I have been on 300 mg for a few months now and I feel like me again! A couple years ago my son was diagnosed with cancer, he beat it, but the fight left me as an empty shell. I didn’t even realize how bad I was struggling just to make it through the day. When I first started Wellbutrin, I thought I had made a mistake, but my husband and I agreed that it would be best to give it a chance. After about 4-5 weeks, everything suddenly seemed better. I have energy, I’m sleeping well, I wake up early and feel rested, my libido is back, and I lost about 10lbs of the weight I put on while my son was sick. I am not just feeling better, I am genuinely enjoying my life. I’m happy, my husband is happy, and life is good. I’m so glad I stuck with it."

10 / 10
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216 Report
  • Dee
  • Taken for 6 months to 1 year
  • December 15, 2019

"I have suffered with anxiety and depression since I was around 16 years old..I am 32 now and I have tried many different antidepressants none of which really helped until I was put on wellbutrin about a year ago. It took a little while of me taking it before I really noticed a difference, but I stuck with it and I am so happy I did. I have completely given up smoking cigarettes (have been smoking regularly since 18) and it has saved my marriage...my mood has changed completely! I feel so thankful for life now and I look forward to the future. Wellbutrin saved my life."

10 / 10
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172 Report
  • Mdchen
  • Taken for 1 to 2 years
  • December 4, 2014

"I suffer from major anxiety to the point where it feels like my chest is going to crush itself from the tension. I also have tendencies to get panic attacks at random times along with a feeling a doom and gloom ever hanging over my head. While I never reached a point of suicidal thoughts I did have weeks and sometimes months of listlessness where I didn't want do anything, see anyone, or be anywhere. I felt like nothing mattered. After being on Wellbutrin I am happy to say these incidents haven't occurred again . Unlike other medicines I have tried in the past, this one has had zero personality effect. I feel like myself, the one who was always trying to bust out of the anxiety ridden zombie that I was."

9 / 10
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289 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.