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Tretten

Generic Name: coagulation factor xiii a-subunit (recombinant) (koe-AG-yoo-LAY-shun FAK-tor THUR-teen)
Brand Name: Tretten

Tretten is used for:

Preventing bleeding in patients with congenital factor XIII (FXIII) A-subunit deficiency.

Tretten is a clotting factor. It works by increasing the amount of clotting factor XIII in the blood, helping the blood form clots and stop bleeding.

Do NOT use Tretten if:

  • you are allergic to any ingredient in Tretten

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tretten:

Some medical conditions may interact with Tretten. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots

Some MEDICINES MAY INTERACT with Tretten. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Factor VIIa because the risk of blood clots may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tretten may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tretten:

Use Tretten as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Tretten. Talk to your pharmacist if you have questions about this information.
  • Tretten is usually given as an injection at your doctors office, hospital, or clinic. If you will be using Tretten at home, a health care provider will teach you how to use it. Be sure you understand how to use Tretten. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Tretten if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Tretten, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Tretten.

Important safety information:

  • Patients receiving clotting factors sometimes develop antibodies or inhibitors to the medicine. This makes Tretten less effective. If Tretten stops working or does not work as well as it has before, contact your doctor immediately for instructions.
  • Tell your doctor or dentist that you take Tretten before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including factor XIII levels, may be performed while you use Tretten. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: It is not known if Tretten can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tretten while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Tretten, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tretten:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; mild pain in the arms or legs; mild pain at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); calf or leg pain, swelling, warmth, redness, or lump; chest pain; confusion; coughing up blood; dizziness; fainting; light-headedness; one-sided weakness; shortness of breath; stomach pain or swelling; sudden, severe headache; unusual bruising or bleeding; unusual weakness; vision or speech changes; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Tretten:

Tretten is usually handled and stored by a health care provider. If you are using Tretten at home, store Tretten as directed by your pharmacist or health care provider. Keep Tretten out of the reach of children and away from pets.

General information:

  • If you have any questions about Tretten, please talk with your doctor, pharmacist, or other health care provider.
  • Tretten is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Tretten or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Tretten. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Tretten. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Tretten.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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