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Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops

Generic name: Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops [ KLOR-oh-ZYE-le-nol/BEN-zoe-kane/HYE-droe-KOR-ti-sone ]
Brand name: Trioxin
Drug class: Otic steroids with anti-infectives

Uses of Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops:

  • It is used to treat ear infections.

What do I need to tell my doctor BEFORE I take Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops?

  • If you have an allergy to chloroxylenol, benzocaine, hydrocortisone, or any other part of this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Chickenpox or a viral ear infection.
  • If you have a hole in the eardrum.

This is not a list of all drugs or health problems that interact with this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops?

  • Tell all of your health care providers that you take this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops). This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may cause harm if swallowed. If this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops) is swallowed, call a doctor or poison control center right away.
  • Do not use longer than you have been told. A second infection may happen.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops) while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops) best taken?

Use this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Keep using this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops) as you have been told by your doctor or other health care provider, even if you feel well.
  • For the ear only.
  • Wash your hands before and after use.
  • Shake well before use.
  • Clean the outer ear before use. Make sure to dry well.
  • Lie on your side with problem ear up.
  • Pull the outer ear outward and upward.
  • For children younger than 3 years of age, pull the outer ear outward and downward.
  • Put drops in ear without touching dropper to ear. Stay on side for 5 minutes.

What do I do if I miss a dose?

  • Use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad ear irritation.
  • Burning.
  • Peeling.
  • Very bad itching.

What are some other side effects of Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Ear irritation.
  • Dryness.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Chloroxylenol/Benzocaine/Hydrocortisone Ear Drops?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep lid tightly closed.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (chloroxylenol/benzocaine/hydrocortisone ear drops), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.