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Capreomycin use while Breastfeeding

Drugs containing Capreomycin: Capastat Sulfate, Capastat

Medically reviewed on September 7, 2017.

Capreomycin Levels and Effects while Breastfeeding

Summary of Use during Lactation

Developmental problems have been reported in two infants exposed to capreomycin in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to capreomycin. Because capreomycin is not orally absorbed it is unlikely to adversely affect the breastfed infant. If capreomycin is required by the mother, it is not a reason to discontinue breastfeeding.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Capreomycin was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.


1. Drobac PC, del Castillo H, Sweetland A et al. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis. 2005;40:1689-92. PMID: 15889370

Capreomycin Identification

Substance Name


CAS Registry Number


Drug Class

Antiinfective Agents

Antibacterial Agents

Antitubercular Agents

Administrative Information

LactMed Record Number



Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

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