My husband takes his blood thinner every morning, yesterday he didn't take it till the evening!
The effect of Xarelto is 8-12 hours but it stays in the blood fot 24 hours. So it is important that you are "covered" at all times, but not double covered. I Always take it at 10PM because at night the risk of having great bleedings is lesser than during the day as there is no specific way to reverse the anticoagulant effect of rivaroxaban in the event of a major bleeding event.
The half-life is 5-9 hours. If you are elderly, greater than 64 y/o, then the half-life is 11-13 hours. Taking the medicine that evening is not a problem. If you are taking this medication for Afib then you should be taking it at night with food. If you are taking this medication for DVT or PE then you should be taking it with food. FDA has granted a breakthrough therapy designation to Portola Pharmaceuticals for its investigational Factor Xa inhibitor antidote, Andexanet Alfa. Keep this in mind if you ever have to go to the ER.
I don't know the significance of taking the same time everyday but I do take mine for PE at 6:30 p everyday since that is the instructions. I will mention though that i forgot one night and remembered it just before going to bed around midnight. Now it could of been coincidence but I had a terrible night. I felt like I had chest flutters, trouble breathing. Maybe it was something else, indigestion from taking it and then laying down but I would not suggest taking before going to bed. I wold rather skip it and take the following day at 6:30 then going thru that again. I was off of Xarelto for 6 days, 3 days before a surgery, 3 days after and no problems. So for me skipping a day wouldn't be a problem.
- Xarelto Information for Consumers
- Xarelto Information for Healthcare Professionals (includes dosage details)
- Side Effects of Xarelto (detailed)
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