Can you take amatryptaline with hydrocodone?

They have a moderate interaction which means:

Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

Interactions between your selected drugs

amitriptyline ↔ hydrocodone
Applies to: amitriptyline, hydrocodone
Using amitriptyline together with HYDROcodone may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience some impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Other drugs that your selected drugs interact with

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