What is the effect of stopping aromasin?

Question posted by monakk on 12 July 2010

Last updated on 9 October 2019 by cancer1945

I will stop taking aromasin in August at the end of 3 years--- took tamoxifen for 2 years before that. Will I experience any changes? I am 62 years old.

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4 Answers

cancer1945 9 Oct 2019

I am a breast cancer 4th stage patent at the Johannesburg public hospital for the past 9 years.
I want to know, after taking tamoxifen for approx 7 years, I discovered I had lung, liver and womb.
Only by having an anagram (blood and mammograms regular tests where useless)
Only found this when my heart was irregular. Even though I had complained for ever that i was tired and no energy (I don't think I had side affects with tamoxifen but it did not prevent me getting more cancer) once I was diagnosed. chemo therapy then on to Accord Anastrozole which I have the worst side effect joint/bone/muscle pain/ extreme tiredness/ trouble sleeping.
So I now have been changed to Amomasin with the same side affects.
So my question is what is the better medication?

Rajive Goel 12 July 2010

Aromasin will not work if one stops taking the med, however your oncologist is a better person to advice so, as he knows your medical history well, hope this helps?.

Inactive 12 July 2010

Patricia Ganz, M.D.: There are no known side effects of stopping this medication. You may notice some benefits if you were having side effects.

Inactive 12 July 2010

Hi , well to be honest after taking it for 3 years I think you should ask your Doctor what are the effects of stop using this med for so long.

monakk 12 July 2010

My oncologist is aware that I am stopping the aromasin. It is his plan. I am just curious.

Inactive 12 July 2010

You should have mentioned that..give me sometime ..let me see what I can come up with ok, and I did do some research, but only found side effects... what we are looking for are withdrawal symptoms... which , I am not 100% certain..there should not be any... but before I answer I must be 100% sure,otherwise it is not good enough!

Inactive 13 July 2010

Hello, I was hoping there were no withdrawal at all.

Remmember I am not a Doctor, I do not have all the answers nor pretend to have them.

Adverse Drug Reactions

The withdrawal rate due to adverse events was in patients with early breast cancer receiving adjuvant treatment with Aromasin® following initial adjuvant tamoxifen therapy. The most commonly reported adverse reactions were hot flushes , arthralgia and fatigue .

The withdrawal rate due to adverse events was in the overall patient population with advanced breast cancer. The most commonly reported adverse reactions were hot flushes and nausea.

Most adverse reactions can be attributed to the normal pharmacological consequences of oestrogen deprivation (e.g. hot flushes).

The reported adverse reactions are listed below by system organ class and by frequency.

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Metabolism and nutrition disorders:
Common Anorexia

Psychiatric disorders:
Very common Insomnia
Common Depression

Nervous system disorders:
Very common Headache
Common Dizziness, carpal tunnel syndrome
Uncommon Somnolence

Vascular disorders:
Very common Hot flushes

Gastrointestinal disorders:
Very common Nausea
Common Abdominal pain, vomiting, constipation, dyspepsia, diarrhoea

Skin and subcutaneous tissue disorders:
Very common Increased sweating
Common Rash, alopecia

Musculoskeletal and bone disorders:
Very common Joint and musculoskeletal pain
Common Osteoporosis, fracture

General disorders and administration site conditions:
Very common Fatigue
Common Pain, peripheral oedema
Uncommon Asthenia

My friend I truly hope you do not experience any of the withdrawal symptoms I have found for you, I do not have all the answers and do not know how long these symptoms last. Bare in mind not all organisms react in the same way... meaning some people may experience withdrawal and others may experience none or some... from a caring individual.

Inactive 13 July 2010

Your question refers to stopping the use of the medication, not what side effects the medication causes. I just wanted to clarify this, so there are no misunderstandings.