Skip to main content

What is an opioid agonist?

Answers

Marvell 4 April 2010

Opioid agonists bind to the opioid receptors and provide pain relief. Morphine is a pure opioid agonist whose principal therapeutic action is analgesia. Other members of the class known as opioid agonists include substances such as oxycodone, hydromorphone, fentanyl, codeine, and hydrocodone. Pharmacological effects of opioid agonists include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, cough suppression, and analgesia. Like all pure opioid agonist analgesics, with increasing doses there is increasing analgesia, unlike with mixed agonist/antagonists or non-opioid analgesics, where there is a limit to the analgesic effect with increasing doses. With pure opioid agonist analgesics, there is no defined maximum dose; the ceiling to analgesic effectiveness is imposed only by side effects, the more serious which may include somnolence and respiratory depression.

https://www.drugs.com/pro/ms-contin.html

Votes: +0
Drugs.com free discount card

Similar questions

How long does naloxone block opiates?

How long does opioid withdrawal last?

How do opioids affect the brain?

Is the Butrans Patch an opioid? Do you gain weight?

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.