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What are the problems when taking suboxone and metoprolol?

Responses (2)

BRRMARS 21 Apr 2011

Okay i checked there two and their is a few warnings, while taking this medication is can cause hypertension, so you need to watch your blood pressure. be careful when standing up or from a lying down position, call a doctor if you start to devlope severe lightheadnedses or tachychardia (i have that), it's where your heart rate is constantly above 100 or more all the time. so please just take it slow and you should be okay, hand in there. if this was at all helpfull please answer yes after this answer, thank you, amber

LaurieShay 21 Apr 2011

Hey mermaid,

I checked your drugs with the interaction checker and this is what it showed:

metoprolol ↔ buprenorphine
Applies to: metoprolol, Suboxone (buprenorphine/naloxone)

MONITOR: Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.

MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.

Other drugs that your selected drugs interact with
•metoprolol interacts with more than 400 other drugs.
•Suboxone (buprenorphine/naloxone) interacts with more than 400 other drugs.
Interactions between your selected drugs and food
metoprolol ↔ food
Applies to: metoprolol

ADJUST DOSING INTERVAL: The bioavailability of metoprolol may be enhanced by food.

MANAGEMENT: Patients may be instructed to take metoprolol at the same time each day, preferably with or immediately following meals.

Hope this helps,

Laurie

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