Trulicity - does the needle hurt?

You bet your bottom it does! I just had it for the 1st time ever today and I saw stars... and the burn... violent stuff!

Heck YAAAA it HURTS!! From 1-10, pain is about 9-10!! From the time the needle punctures the skin until all the medicine penetrates under the skin, which lasts for about 10 seconds, it is so painful!! The initial punch of the needle hurts so bad & you can literally feel the medicine go through the skin because it is stinging and burning at the site every single second! Although the pain diminishes within a few minutes, the manufacturer's design failed to focus on delicasy. Compared to other biological self-injections, my Humira pen rates about 1-2 for pain & Ozempic with no pain level. This is the absolute most painful weekly injection I've ever experienced & tbh I DREAD it. People say to numb the injection site with an ice cube beforehand. Never tried bc I'd rather just get it over with & not bother.

Doesn't hurt in the least bit.
You will see a small speck of blood where needle penetrates the skin.
I've been using Trulicity for almost a year.
Easy smeasy

It usually hurts me. It was nearly intolerable until my doctor instructed me how to do it. You DON'T press hard on your stomach so the drug goes into your abdominal muscles! Lightly pinch an inch of fat from your mid section and inject into that fat. Much less pain. My dr also said Trulicity is also thicker than other injectables, so will hurt more. But everyone is different. If Trulicity hurts, get samples of similar drugs from your doctor, and try them until you find the most tolerable. Doctors these days seem just to want to get you on the drug, then out of the office so they can get to the next patient, etc. Don't accept the bum's rush from them. There are many alternatives to most drugs, and you need to find the one that's best for you.

For me the only time it hurt was when I pressed the injector too firmly against my belly.

Like heck it doesn’t hurt. I’ve sat Thru deep root planing my whole mouth in 1 day no numbing - this injection hurts! Don’t care if it’s warm or cold. I gave myself regular syringe injections of B-12 in my thigh for a year, barely felt it. This hurts during and for an appreciable amount of time later. Cruise the net, I’m one of MANY who have the same experience.

Sometimes it may sting for a nano-second but that's all. I take it out of the frig an hour before I inject it and that seems to help. I also spray a small amount of a numbing substance I got from Amazon that makes my skin very cold and that helps block the pain. The benefits from Trulicity are so worth it for me.

I just took my first Trulicity shot. I was so afraid , and truthfully did not feel a thing Tiny poke . I set the pen out for 30 minutes to warm up and injected in my tummy.

No, it doesn’t really hurt at all. It may sting for just a few seconds but that’s it. Injecting into your lower abdomen is probably the least painful site.

I chuckled at the response where they described it as “impaling” your skin and blood after the needle withdraws. I guess that’s all subjective because I NEVER have as much as a pin head of blood and I can barely feel the needle prick the skin. A total of 30 seconds and you won’t even know you’ve had the injection.

No reason to be concerned or afraid.

Yes , it does hurt.

The Trulicity injector pen definitely hurts. The needle used is much bigger than other needles I have used. Once you unlock the pen and press the button the needle comes down and enters your skin. This injection is so bad that I actually think the appropriate term is impale. Then it pumps the drug in pretty fast. So fast that it created a lump and irritation at the injection site. The worst was the blood. There was a good amount of bleeding once the needle retracted and whole process was done. My injection site was my thigh and was the same place I had injected my previous medication. So this is not like I have not done this before or chose a different location. Your mileage may vary, but this was my unfortunate experience.

I have used Trulicity for a few years now. It is painless as the needle penetrates, but I experience a very, very slight sting as the needle withdraws itself.

It's not insulin. Its a once a week shot so it's probably a thicker Liquid. I think you can deal with a once a week. Shot if it hurts a little.