I know you shouldn't take the two at the same time but if I take a tizanidine at noon, can I take a trazodone 6-8 hours later without risk of the heart effects?
Trazodone and tizanidine together?
Question posted by Crystlew123 on 25 May 2021
Last updated on 25 May 2021 by WildcatVet
Yes, that's likely safe but to be sure you should ask your doctor or pharmacist.
Tizanidine has a short half life of about 2.5 hours meaning that after 2.5 hours about 50% of your dose remains in your system, after 5 hours only 25% remains, etc.
If you can make it 7-8 hours you should be okay.
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