What does translingual route mean?

Hi Marcia,
My friend Masso gave you a good answer.
In different ares it's also called sublingual. The mouth is very vascular (it's why it bleeds so much) so it's a faster route for pills to be absorbed into the system as Masso explained.
A good example is nitro for chest pain. It is placed under the tongue and melts.
:-)

Translingual-Drug absorption through the tongue into systemic circulation after application on the tongue (spray).