I've been taking Methotrexate for two years now, and I still suffer from the side effects every week. I feel more tired than I ever have before, and this lethargy has caused me to gain weight and become somewhat depressed. I'm normally a very active and energetic person and I don't like this change. Am I the only person who feels this way on MTX?
My boyfriend doesn't talk about how he feels taking this but I can tell you this. He is irritable, we aren't picking on each other or laughing much. Just seems kinda rutish dull place we are in. This post doesn't give me much hope it will get better. His biggest symptoms right now are his stomach being tore up after taking it and being grumpy. It hadn't kicked in yet. Only been on it 7 weeks and supposed to take 8 to work. I'm praying his RA improves to a point it helps with the down coming from this.. my blood pressure is getting bad due to inactivity so to speak. I wish you luck and I will follow your post as I am hoping for a miracle here.
My son has just started Methotrexate again after a break from it for a few years. He is very very tired all the time spends half of his day in bed sleeping.
It helps a small bit of his psoriasis, but not where it is at its worst in his groin.
It doesn't seem to have much effect on his arthritis probably would if he took more. But after you have had your liver damaged by it he is keeping to a low dose. He does seem to have a flare up after getting excited watching the football. Does anybody else have flare up after getting excited.
I'm only on MTX about 8 weeks and I'm so tired and worn out. Have 3 kids and just is so hard to motivate myself. It makes it worse when some days I wake up feeling great and full of life so I can remember what I used to be like. The day I take my MTX I'm useless, I find I can't think straight and couldn't make a full sentence sometimes. Does it get better because I still ache although not as bad. Just feeling fed up.
I too am on methotrexate and I don't remember what it used to be like to get through a day with energy. I feel I struggle through every day just to do the basic things. It does get me down but because I can't seem to function not because I am depressed. I feel useless and just so not normal. It is not normal to be hardly able to pick the kids up from school or do some simple housework...
I drag myself around and feel I am always pushing myself. I have gotten to the point that I am embarrassed about how tired I am and even lie to my husband and my kids about how much sleeping I am having to do. I feel like an idiot most of the time and feel as though maybe I am just making it up or am lazy or something but I get up wanting to do things with my day and make lists but I just can't.
It has gotten to the point where I was actually jealous of my best friend for being diagnosed with severely high diabetes because at least there was a reason for her fatigue.
My blood tests are all perfect and my disease is under control.
For the people out there who say, don't worry about it, think about how it would feel to not be able to achieve anything in a day. Not feel good about what you've been able to do, all day, every day, always. It feels as though I amount to nothing... I HATE it so much.
(I also take prednisone).
Is it me, or is it this stuff that makes me tired. Maybe its because I am surrounded with people who don't want to acknowledge, even though I am currently well, that I have a life threatening rare auto immune disease think that, seeing that I am not sick, I should be able to do what everybody else does. I feel pressure all the time and I just can't keep up.
I am sick of saying 'mummy's just gonna have a lay down', or 'I'm sorry but I'm just too tired' or telling the kids that they can't have their friends over cause I need to sleep.
Is it just me or would this stuff really make me tired!!!
I take 12 different tablets every day. I mean, come on!!!
I have been taking methotrexate for over a year, now. It makes me feel like crap.
I have no appetite when I take it and take zofran to prevent nausea.
I have a genetic form of uveitis. I skipped a dose and feel GREAT.
Maybe it would be better to be blind and feel ok than to feel bad all the time.
I inject 20 mg a week. I asked for the injectable because the pills are way worse.
Hello everyone I have to say that this drug is pretty strong and does cause a lot of side effects but be honest with you when I don't inject it I feel the difference and the pain in my joints and bones is worst so unfortunately I have to deal with the unpleasant side effects,for example last 2 week's I had to skip it because I got an Infection and the doctor prescribed Augmentin and told me not to use the Methotrexate because it would interfere with the antibiotics and by the 2nd week I was in so much pain I couldn't wait to finish the antibiotics. I have on this medicine for about a year first pills but my fatigue was worst so I switched to the injectable form which it makes the down time shorter,I also gained a few extra pounds since I started this medicine, I would recommend to keep talking to your doctor and making sure you boost your immune system with folic acid,vitamin C and multivitamins like I said under doctor supervision of course. Take care guys and keep hoping to get better.
I just completed 1 cycle of methotrexate. I m feeling sleepy all d time . Getting very tired day by day... I m 30 yrs old ... i dont know how to handle myself mentally and physically... I m tired of complaining to anyone... but still have faith... that one day i will be happy as before ...
I have been taking this medication for the least 2 months and for the 48 hours after I am just wanting to sleep, I cannot think straight and literally sit at work wondering when I can go home and go to sleep, also my RA has not gotten any better! I am seeing a specialist next week so going to get them to look into this. I cannot feel this bad and still feel no better. Fed up and ruining my life atm.
- Methotrexate Information for Consumers
- Methotrexate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methotrexate (detailed)
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