Because I occasionally have trouble remembering to take both doses, my Dr recently switched me to the ER formulation, prescribing ONE 500mg ER tablet daily.
She states this is the same dose as I had previously because the ER formula "keeps 500mg active in your system all day". This just doesn't sound right to me.
Is the dosing for 500 mg ER once daily equivalent to 500mg (immediate release) twice daily or has my dose been cut in half?
I have been taking metformin 500mg (immediate release) twice daily for one year?
Question posted by jamiekb on 24 Dec 2014
Last updated on 24 December 2014 by kaismama
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Answers
kaismama
24 Dec 2014
Yea I'm pretty sure you need a gram of the er to equal 500 twice a day. Here is what is in the prescribing info for the extended release... In randomized trials, patients currently treated with immediate-release metformin were switched to metformin hydrochloride extended-release tablets. Results of this trial suggest that patients receiving immediate-release metformin treatment may be safely switched to metformin hydrochloride extended-release tablets once daily at the same total daily dose, up to 2500 mg once daily. Following a switch from immediate-release metformin to metformin hydrochloride extended-release tablets, glycemic control should be closely monitored and dosage adjustments made accordingly
Get your pharmacist to weigh in on it with your dr.
Keep a good record of your blood sugar daily. If its going up every day, call your dr. Don't wait until its sky high, if you see an increase every day, call.
FoorYoonA
24 Dec 2014
500mg means 500mg inters your body/day whatever it stays for 1hr or 24hr; the effect must be the same. So you've been taken 1g/day in divided 2 doses, supposed to be 1g in one dose of ER tabs.
Related topics
diabetes, type 2, metformin, dosage, formulation, tablet
Further information
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- Side effects of Metformin (detailed)
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