Can I take diet pills with prednisone?

Hello, I recommend asking your doctor. Another thing you could do on your own is to use the Interaction Checker here on this site: https://www.drugs.com/drug_interactions.html and discuss your findings with your doctor.

Prednisone is notorious for causing weight gain so maybe a dosage adjustment is in order and I wouldn’t attempt that without a doctor’s guidance because you should have your adrenal glands checked for adrenal insufficiency. Be safe and I’m glad you’re asking first.

Source: Personal experience. I’ve been on low dose prednisone since 2015.