After reading more info. on this drug, and understanding what it does. Whilst taking the tablet with grapefruit juice is such a dangerous combination, Does that include all citrus fruit juice's, Like fresh orange, tropical/exotic fruit juices, etc.. Would there be any danger with others fruit juices.
Am on tac for two years. No grapefruit juice. It causes a malabsorption and you are not getting the right dose when you drink it. As you know, the tac has to be constant to do its job.
Other juices are fine as long as they are not holding a mix of it. Reading the label is my best bet.
Good luck with it.
YES! Lime juice, starfruit, and pomegranate are a few others. If you look hard enough, you will find data on them in small studies from academic institutions. Like grapefruit, they inhibit the Cytochrome P450 system in the liver which metabolizes Tacrolimus and some other drugs, causing increased and possibly toxic levels of Tacrolimus in the body. In my opinion, these data have not been added to the official prescribing information for the drug because it is now generic, and, therefore, nobody is incentivised to do so.
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