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FDA Approves First Generic Version of Sabril to Help Treat Seizures in Adults and Pediatric Patients with Epilepsy

Posted 21 hours ago by Drugs.com

January 16, 2019 – The U.S. Food and Drug Administration approved the first generic version of Sabril (vigabatrin) 500 mg tablets for treating complex partial seizures, also called focal seizures, as an adjunctive therapy (given with another primary treatment) in patients 10 years and older who have responded inadequately to several alternative (refractory) treatments."Prioritizing the approval ...

Rough Neighborhood, Worse Epilepsy?

Posted 4 Dec 2018 by Drugs.com

TUESDAY, Dec. 4, 2018 – Living in a high-crime neighborhood may make epilepsy worse, a small study suggests. Researchers at the University of Illinois at Chicago looked at 63 epilepsy patients in Chicago. Residents of high-crime neighborhoods had significantly more seizures than residents of safer areas, the study found. "On average, people in high-crime neighborhoods had three seizures versus ...

Benefits of CBD Liquid for Epilepsy May Fade With Time: Study

Posted 2 Dec 2018 by Drugs.com

SUNDAY, Dec. 2, 2018 – A marijuana-derived drug that helps control epileptic seizures appears to become less effective over time in some patients, a new Israeli study reports. Cannabidiol (CBD) liquid has been proven effective against seizures, but about one-third of patients develop tolerance that blunts the drug's effectiveness, according to research presented Sunday at the American Epilepsy ...

Sudden Death Risk in Epilepsy Can Wane Over Time

Posted 2 Dec 2018 by Drugs.com

SUNDAY, Dec. 2, 2018 – The risk of sudden unexpected death in people with epilepsy can change over time, and it usually changes for the better, a new study reports. In what the researchers are calling hopeful news, the study found that people who have a medium or high risk of sudden unexpected death in epilepsy (SUDEP) often don't remain at the same risk level. "This analysis shows that there is ...

Depression Is a Risk for Teens, Adults With Epilepsy

Posted 2 Dec 2018 by Drugs.com

SATURDAY, Dec. 1, 2018 – Teens and adults with epilepsy are at increased risk for depression and should undergo regular screening, two new studies say. In one study, researchers evaluated nearly 400 teens, ages 15 to 18, with epilepsy. They found that 8 percent had moderate or severe depression and another 5 percent had attempted suicide or thought about it. An additional 22 percent of teens ...

Anti-Seizure Drug Potiga (ezogabine) May Be New Weapon Against Depression

Posted 1 Nov 2018 by Drugs.com

THURSDAY, Nov. 1, 2018 – A drug used to control seizures may be a potent weapon against depression in patients who don't find relief with antidepressants, a small pilot study suggests. Some of the 18 patients taking ezogabine (Potiga) experienced a 45 percent reduction in depression and an increase in their ability to feel pleasure, as well as an increase in resilience and the capacity to ...

Internal Body Clocks May Affect Timing of Epileptic Seizures

Posted 13 Sep 2018 by Drugs.com

THURSDAY, Sept. 13, 2018 – Circadian rhythms, the 24-hour body clocks that regulate a person's sleep-wake cycle, may affect the timing of seizures in roughly 80 percent of epilepsy patients, researchers report. These findings, which shed new light on seizure patterns, could help doctors treat the disease more effectively, the researchers said. "Understanding the cyclic nature of diseases is ...

Health Tip: Keep Your Epileptic Child Safer

Posted 31 Aug 2018 by Drugs.com

-- Parents of a child with epilepsy may be preoccupied with keeping the child safe during the school day. The U.S. Centers for Disease Control and Prevention offers these suggestions: Develop an action plan so that teachers and school officials know what to do in the event of a seizure or similar emergency. Contact the Epilepsy Foundation, which offers free training programs for school staff. ...

Brain Implant Puts the Brakes on Epileptic Seizures in Mice

Posted 31 Aug 2018 by Drugs.com

THURSDAY, Aug. 30, 2018 – Experiments in mice have shown that an implanted electronic device in the brain can detect – and deliver drugs to stop – impending epileptic seizures. Potentially, a similar device might help people with epilepsy, Parkinson's disease and brain tumors who have failed standard treatment. So far, the technology is in the very early stages of development and its clinical ...

FDA Approves Diacomit (stiripentol) for Seizures Associated with Dravet Syndrome

Posted 22 Aug 2018 by Drugs.com

On August 20, 2018, the U.S. Food and Drug Administration (FDA) approved Diacomit (stiripentol) for seizures associated with Dravet syndrome in patients 2 years of age and older taking clobazam. Dravet syndrome is a rare genetic condition that usually appears during the first year of life with prolonged fever-related seizures. Later, other types of seizures typically appear, and additionally, ...

FDA Approves Diacomit (stiripentol) for Seizures Associated with Dravet Syndrome

Posted 22 Aug 2018 by Drugs.com

On August 20, 2018, the U.S. Food and Drug Administration (FDA) approved Diacomit (stiripentol) for seizures associated with Dravet syndrome in patients 2 years of age and older taking clobazam. Dravet syndrome is a rare genetic condition that usually appears during the first year of life with prolonged fever-related seizures. Later, other types of seizures typically appear, and additionally, ...

Brain's 'Plasticity' Amazes as Boy Recovers From Drastic Surgery

Posted 31 Jul 2018 by Drugs.com

TUESDAY, July 31, 2018 – The developing brain of a growing child has incredible ways of compensating for the loss of an essential brain region, a new case study shows. A young boy has retained his ability to recognize faces even though surgeons removed one-sixth of his brain, including the region that normally handles that task, his doctors said. Essentially, the other side of the 10-year-old's ...

FDA OKs First Drug Epidiolex (Cannabidiol) Containing Marijuana-Derived Ingredient

Posted 25 Jun 2018 by Drugs.com

MONDAY, June 25, 2018 – In a regulatory first, the U.S. Food and Drug Administration on Monday said it had approved a drug with an ingredient derived from the marijuana plant. In a statement, the agency said it had "approved Epidiolex [cannabidiol, or CBD] oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet ...

Low Dose of CBD Oil Eases Epilepsy Seizures: Study

Posted 17 May 2018 by Drugs.com

WEDNESDAY, May 16, 2018 – Less appears to be more when it comes to treating epilepsy with the marijuana extract cannabidiol, a new clinical trial suggests. Patients taking a 10-milligram (mg) daily dose of pharmaceutical grade cannabidiol (CBD) experienced nearly as great a reduction in seizures as patients on 20 mg, and with fewer side effects, said lead researcher Dr. Orrin Devinsky. He is ...

Study Debunks Idea That Epilepsy Can Hamper Fertility

Posted 30 Apr 2018 by Drugs.com

MONDAY, April 30, 2018 – Having epilepsy doesn't appear to lower a woman's chances of becoming pregnant, new research finds. "Our paper is a myth-buster," said study author Dr. Page Pennell, director of research in the division of epilepsy at Brigham and Women's Hospital in Boston. "When I entered this specialty, there were a lot of myths and stigma about women living with epilepsy," Pennell ...

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