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Epilepsy News

Chronic Disease in Mom May Be Linked to Newborns' Heart Disease

Posted 15 days ago by

TUESDAY, Oct. 11, 2016 – Babies born to mothers with certain chronic diseases may be at increased risk for heart problems, a new study suggests. The analysis included millions of births in Taiwan. The researchers found that pregnant women who themselves had been born with heart defects or who later developed type 2 diabetes were more apt to have babies born with severe heart disease ("congenital" disease). The study didn't prove a cause-and-effect link. However, babies of mothers with these conditions should be closely monitored after birth, according to the researchers. The investigators said they also found a slightly higher risk of mild congenital heart problems in babies of mothers with several other chronic diseases, including: type 1 diabetes, high blood pressure, anemia and epilepsy. "Although some maternal diseases were associated with congenital heart disease in offspring, ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Seizures, Hypertension, Heart Disease, Epilepsy, Anemia, Ischemic Heart Disease, Hypertensive Heart Disease, Labor and Delivery including Augmentation

FDA Approves Carnexiv (carbamazepine) injection as Intravenous Short-Term Replacement Therapy for Certain Seizure Types

Posted 16 days ago by

DEERFIELD, Ill.--(BUSINESS WIRE) October 07, 2016 --Lundbeck announced today that the U.S. Food and Drug Administration (FDA) has approved Carnexiv (carbamazepine) injection as a short-term replacement therapy for oral carbamazepine formulations in adults with certain seizure types when oral administration is temporarily not feasible. Carnexiv received orphan drug designation for this indication and will be the first available intravenous (IV) formulation of the antiepileptic drug (AED) carbamazepine. Lundbeck plans to make Carnexiv commercially available in the United States in early 2017. Carnexiv is a short-term (≤7 days) intravenous replacement therapy for oral carbamazepine formulations that provides continuity of care for adult patients who are unable to take carbamazepine by mouth and have the following seizure types: Partial seizures with complex symptomatology Generalized t ... Read more

Related support groups: Seizures, Epilepsy, Carbamazepine, Seizure Prophylaxis, Carnexiv

Newer Epilepsy Drugs May Be Safer During Pregnancy

Posted 1 Sep 2016 by

THURSDAY, Sept. 1, 2016 – Women who take the new epilepsy drugs levetiracetam and topiramate during pregnancy don't run the risk of harming their infant's mental development, British researchers report. But the commonly prescribed anti-seizure drug valproate was linked with lower IQs in children, especially when taken at higher doses, researchers say. "The treatment of epilepsy in women who are considering a pregnancy or are pregnant involves optimizing the health of the mother as well as keeping the risk to the fetus as low as possible," said lead researcher Rebecca Bromley, a research fellow at the Institute for Human Development at the University of Manchester. In the study, children exposed to levetiracetam (Keppra) or topiramate (Topamax) in the womb did not differ from children not exposed to these drugs. And they had better outcomes than the children exposed to valproate ... Read more

Related support groups: Birth Control, Contraception, Emergency Contraception, Seizures, Topamax, Epilepsy, Keppra, Topiramate, Qsymia, Postcoital Contraception, Seizure Prevention, Levetiracetam, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Keppra XR, Seizure Prophylaxis, West Syndrome, Status Epilepticus, Lennox-Gastaut Syndrome, Trokendi XR, Topamax Sprinkle

FDA Medwatch Alert: Lamotrigine Orally Disintegrating Tablet 200 mg by Impax: Recall - Incorrect Labeling of Blister Cards

Posted 31 Aug 2016 by

ISSUE: Impax Laboratories, Inc. issued a voluntary nationwide retail level recall on August 19, 2016 for one lot of Lamotrigine Orally Disintegrating Tablet (ODT) 200 mg, NDC 0115-1529-08, Lot # 502240. The affected lot was distributed between June 13, 2016 and August 10, 2016 to wholesale distributors and retail pharmacies nationwide.  Unit-of-use blister packs (a 10 count blister card contained in a single plastic shell-pack) may contain 100 mg product instead of 200 mg product.  Each blister card within the unit-of-use blister pack is properly labeled as 100 mg ODT, however the plastic shell pack containing the 100 mg blister cards is labeled as 200 mg ODT. Shell-packs from the affected lot may contain 100 mg ODT instead of 200 mg ODT, and as a result, it is possible that consumers could take less than their intended lamotrigine dose. A reduction in dose may lead to reduced t ... Read more

Related support groups: Seizures, Lamictal, Epilepsy, Lamotrigine, Lamictal XR, Lamictal Blue, Lamictal Orange, Lamictal CD, Lamictal ODT, Lamictal Green

Young People With Epilepsy Struggle on Many Fronts

Posted 10 Aug 2016 by

WEDNESDAY, Aug. 10, 2016 – Children and young adults with epilepsy face an array of psychological, physical and social challenges, a new analysis reveals. Australian researchers reviewed 43 studies that included a total of more than 950 children, teens and young adults, and delved into their experiences with the seizure disorder. "Children with epilepsy feel vulnerable from a physical and a social perspective," said study author Deepak Gill. He is a pediatric neurologist who heads the Children's Comprehensive Epilepsy Service at the Children's Hospital of Westmead, in New South Wales. "One theme that came out was the loss of bodily control, and that the person during a seizure can feel physically overpowered, with worry that the seizures would lead to serious injury," Gill added. Those with epilepsy also reported feeling inferior and discriminated against. Some of the comments from the ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis, West Syndrome, Status Epilepticus, Lennox-Gastaut Syndrome

4 Out of 5 Kids With Epilepsy Have Other Health Problems: Study

Posted 1 Aug 2016 by

MONDAY, Aug. 1, 2016 – Nearly 80 percent of children who have the seizure disorder epilepsy also have other health conditions, such as digestive troubles and attention-deficit/hyperactivity disorder, a large Norwegian study finds. "Parents should be aware of the increased risk of [other] problems for their children," said study author Dr. Richard Chin. Epilepsy is a chronic seizure disorder. It is estimated that nearly 4 million people in the United States have epilepsy, according to the U.S. Centers for Disease Control and Prevention. The new study included health information on more than a million Norwegian children from 2008 through 2013. About 6,600 of the children had a diagnosis of epilepsy, the researchers said. The data showed that nearly four out of five children with epilepsy had at least one other health issue. These included medical, neurological, developmental or ... Read more

Related support groups: Seizures, Attention-Deficit Hyperactivity Disorder (ADHD), Asthma, Epilepsy, Indigestion, Seizure Prevention, Seizure Prophylaxis, Brain Anomalies incl Congenital, Reversible Airways Disease, History of Musculoskeletal Disorder, Executive Function Disorder

Helping a Child Manage a Chronic Illness

Posted 21 Jul 2016 by

THURSDAY, July 21, 2016 – Children and teens who feel confident handling a chronic illness on their own appear better able to learn to manage their health as adults, a new study finds. The University of North Carolina investigators concluded that kids who believe their health is controlled by adults or by chance may not develop the health self-management skills they will need as adults. This could put them at increased risk for health problems. The study included 163 youngsters, aged 6 to 17, attending a camp for young people with chronic diseases. Researchers asked the participants whether they felt they had control over their health. The researchers also assessed whether the children took medications as prescribed and their readiness to transition to adult care. Feeling confident about managing their own health and being ready to transition to adult care likely indicate that ... Read more

Related support groups: Seizures, Asthma, Epilepsy, Asthma - Maintenance, Diabetes, Type 1, Seizure Prevention, Asthma - Acute, Seizure Prophylaxis, Allergic Asthma, Reversible Airways Disease - Maintenance, Reversible Airways Disease

Epilepsy May Triple ADHD Risk, Danish Study Finds

Posted 13 Jul 2016 by

WEDNESDAY, July 13, 2016 – Children who suffer from epilepsy or fever-related seizures may face a higher risk of also having attention-deficit/hyperactivity disorder (ADHD), new Danish research suggests. The findings echo those of some previous research. But, U.S. experts said the new study is notable because of the large number of study participants – nearly 1 million – and the length of follow-up, which was up to 22 years. The study looked at children born in Denmark from 1990 through 2007, tracking them until 2012. The investigators found those with epilepsy seemed to have nearly three times the risk of developing ADHD compared to children without epilepsy. And children who had fever-related seizures appeared to have an almost 30 percent increased risk of ADHD. Children with both epilepsy and fever-related seizures had a risk of ADHD more than three times higher than those without ... Read more

Related support groups: Seizures, Attention-Deficit Hyperactivity Disorder (ADHD), Fever, Epilepsy, Oppositional Defiant Disorder, Seizure Prevention, Seizure Prophylaxis, Executive Function Disorder

Genetic Insights May Help Kids Battling Developmental Delays

Posted 26 May 2016 by

WEDNESDAY, May 25, 2016 – There's new hope for children stricken by mysterious developmental delays, with a new study showing that extensive genetic analysis may help determine the cause of their disability. Canadian researchers found a precise genetic cause for seven out of every 10 children suffering from a previously undiagnosed condition that caused developmental delays. In many cases, the genetic analysis led to groundbreaking discoveries. Researchers discovered 11 new disease genes linked to developmental delays, and described new physical traits and symptoms for a number of known diseases. And based on the new genetic diagnosis, doctors were able to offer targeted treatments in four of 10 cases, said senior researcher Dr. Clara van Karnebeek. She is a pediatrician and biochemical geneticist at BC Children's Hospital and principal investigator with the Center for Molecular ... Read more

Related support groups: Epilepsy, Autism, Vitamin/Mineral Supplementation and Deficiency, Lennox-Gastaut Syndrome, Diagnosis and Investigation

Pain, Epilepsy Drug Lyrica May Increase Birth Defects Risk, Study Suggests

Posted 18 May 2016 by

WEDNESDAY, May 18, 2016 – The widely prescribed drug pregabalin (Lyrica) may slightly increase the risk for birth defects, a new study suggests. In a small study, researchers found that among women taking Lyrica during the first trimester of pregnancy, 6 percent had infants with major birth defects. In women who weren't taking the drug, 2 percent had a baby with a major birth defect, the study found. "These results should be taken with caution," said study senior author Dr. Thierry Buclin, from the Swiss Teratogen Information Service and the division of clinical pharmacology at the Lausanne University Hospital, in Switzerland. "It's a warning, but it cannot be taken as a certainty." Lyrica is prescribed for a range of health problems, including epilepsy, fibromyalgia and anxiety. The new study findings should be investigated further, Buclin said. "We should not unduly alarm ... Read more

Related support groups: Birth Control, Anxiety, Generalized Anxiety Disorder, Contraception, Anxiety and Stress, Fibromyalgia, Seizures, Lyrica, Social Anxiety Disorder, Epilepsy, Pregabalin, Delivery, Performance Anxiety, Hydrocephalus, Premature Labor, Brain Anomalies incl Congenital, Labor Pain, Cesarean Section, Apnea of Prematurity, Labor and Delivery including Augmentation

Eisai Announces FDA Approval of Fycompa (perampanel) Oral Suspension

Posted 2 May 2016 by

WOODCLIFF LAKE, N.J., May 2, 2016 /PRNewswire/ – Eisai Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Fycompa (perampanel) CIII Oral Suspension as adjunctive therapy for the treatment of partial-onset seizures (POS) with or without secondarily generalized seizures, and primary generalized tonic-clonic (PGTC) seizures in patients with epilepsy 12 years of age and older. The oral suspension formulation is a bioequivalent, interchangeable alternative to the Fycompa tablet formulation, and is expected to be available to patients in June 2016. "We are excited about the approval of Fycompa Oral Suspension, as it gives another option to patients with epilepsy who may have difficulty swallowing tablets or prefer liquids," said Lynn Kramer, M.D., Chief Clinical Officer and Chief Medical Officer, Neurology Business Group, Eisai. "The development of this new ... Read more

Related support groups: Seizures, Epilepsy, Fycompa, Perampanel

One-a-Day Anti-Seizure Drug Shows Promise for People With Epilepsy

Posted 15 Apr 2016 by

THURSDAY, April 14, 2016 – A once-daily epilepsy drug may control seizures just as well as a twice-daily drug, researchers report. Their preliminary study compared the once-a-day drug eslicarbazepine acetate (Aptiom) to the twice-daily drug carbamazepine (Tegretol, Carbatrol) for more than 800 people newly diagnosed with partial seizures, which originate in one area of the brain. After six months, 71 percent of those taking eslicarbazepine and 76 percent of those taking carbamazepine were seizure-free. After one year, 65 percent of those taking eslicarbazepine and 70 percent of those taking carbamazepine were seizure-free, said the team led by Dr. Elinor Ben-Menachem, of Gothenburg University in Sweden. The study was funded by Portuguese drug maker BIAL-Portela & Ca., and will be presented April 19 at the American Academy of Neurology's annual meeting, in Vancouver. "Seizure control is ... Read more

Related support groups: Seizures, Epilepsy, Tegretol, Carbamazepine, Seizure Prevention, Tegretol XR, Seizure Prophylaxis, Epitol, Carbatrol, Equetro, Aptiom, Eslicarbazepine

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects

Posted 6 Apr 2016 by

WEDNESDAY, April 6, 2016 – Despite initial concern from early studies, taking the epilepsy drug lamotrigine (Lamictal) during pregnancy may not raise the risk for certain birth defects, a large new study finds. "An initial study of this drug showed an increased risk for cleft lip or cleft palate, but a number of other studies since have not, and our previous study showed an increased risk of clubfoot," said study author Helen Dolk, of Ulster University, in Northern Ireland. However, the new study, which had "a much larger population size – more than double the size of our previous study" – has found no significant links, Dolk said in a news release from the journal Neurology. The research, funded by the drug's maker, Glaxo Smith Kline, was published April 6 in the journal. In addition to being prescribed to control epileptic seizures, lamotrigine is used to prevent mood swings in ... Read more

Related support groups: Birth Control, Contraception, Seizures, Lamictal, Epilepsy, Lamotrigine, Seizure Prevention, Delivery, Lamictal XR, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Seizure Prophylaxis, Premature Labor, Brain Anomalies incl Congenital, Lamictal Blue, Cesarean Section, Lamictal Orange, Labor Pain, Lamictal CD, Lamictal ODT, Labor and Delivery including Augmentation

Type 1 Diabetes Linked to Epilepsy Risk, Study Suggests

Posted 1 Apr 2016 by

THURSDAY, March 31, 2016 – People who have type 1 diabetes may be nearly three times more likely to develop the seizure disorder epilepsy than people without type 1 diabetes, a new study suggests. The youngest people with type 1 diabetes – under 6 years old – seemed to be six times more likely to develop epilepsy, the researchers reported. But, those with the highest risk of epilepsy appeared to be children with type 1 diabetes who had to be treated in a hospital for a severe low blood sugar (hypoglycemia). The study found the risk of epilepsy was 16.5 times higher for these children. It should be noted, however, that the study did not establish a cause-and-effect relationship between the two conditions. And the "absolute" risk of any one person with type 1 diabetes going on to develop epilepsy remains very small. Epilepsy is a brain disorder affecting less than 1 percent of the U.S. ... Read more

Related support groups: Seizures, Insulin, Epilepsy, Diabetes, Type 1, Seizure Prevention, Seizure Prophylaxis

Even Controlled, Epilepsy May Still Cause Problems for Kids

Posted 31 Mar 2016 by

THURSDAY, March 31, 2016 – Even when their seizures are well-controlled, children with epilepsy can still have learning and behavioral disorders that lead to social and educational problems when they're young adults, a new study finds. "Frequency and intensity of seizures remain important predictors of how well a child does into adulthood. But, somewhat to our surprise we also found seizures are by no means the sole influencers of social and educational outcomes among adults with childhood epilepsy," said study lead author Anne Berg. Berg is a scientist with the Ann and Robert H. Lurie Children's Hospital of Chicago, and professor of pediatrics and neurology at Northwestern University Feinberg School of Medicine. The research included 241 children and teens in Connecticut who were diagnosed with uncomplicated epilepsy from 1993 to 1997. They were followed for an average of 12 years. ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis, West Syndrome, Status Epilepticus, Lennox-Gastaut Syndrome

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Seizures, Status Epilepticus, Lennox-Gastaut Syndrome, West Syndrome, Central Nervous System Disorders

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gabapentin, Lyrica, Lamictal, Neurontin, Depakote, Keppra, lamotrigine, Tegretol, Dilantin, view more... Trileptal, pregabalin, carbamazepine, Depakote ER, levetiracetam, oxcarbazepine, Diamox, phenytoin, divalproex sodium, Tegretol XR, Lamictal XR, valproic acid, acetazolamide, Keppra XR, Epitol, Carbatrol, Depakote Sprinkles, Mebaral, Depakene, Diamox Sequels, Fycompa, Phenytoin Sodium, Potiga, Stavzor, Felbatol, Oxtellar XR, mephobarbital, Spritam, perampanel, Phenytek, Lamictal ODT, blue cohosh, vigabatrin, Lamictal CD, Carnexiv, Peganone, Elepsia XR, Roweepra, felbamate, Depacon, Cerebyx, ezogabine, fosphenytoin, Sabril, Fanatrex, ethotoin