... starting to feel very dizzy, tingling sensations, brain fog, and nauseous. Is there anything I can do (without taking another prescription) to lessen the side effects? I started Effexor 6 years ago for depression and anxiety while going through a divorce. Life is much more stable now and I really want to go off of this medicine.
I just started weaning off of Effexor XR 150 mg. I am now on day 2 of no Effexor at all. I am?
Question posted by FrankieH4me on 25 Jan 2016
Last updated on 11 March 2024 by Celtwoman52
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
13 Answers
Hi, am 72 and have been weaning off my effexor XL for 3 months now. Have been on it for several years. 150mg to 75mg and it's been are perfect words!! Much less so now. Was experiencing great fatigue and that's begun to dissipate. The reason I want off of this med as well as trazodone (used for sleep) is since Sept 2023 I began to move from vegan foods to whole food plant based. I'm totally committed to my new healthy eating and my body has transformed as well as brain fog lifted. I'm learning so much about how bad processed foods are and the impact it has on our whole being. Anyway, my body metabolizes foods and medications differently especially as I have aged. I'm feeling so much better and have incorporated daily walking and other quality 'fun' stuff. Good luck to those who want to wean off.
I have been on Effexor for many years and have been weaning over the past several years. I am down to 75mg, but still have horrible dizziness, weird auditory effects, have panick attacks if I miss a dose. I have yet to be able to get this to go away without taking another dose. Over the past year, I get these symptoms occasionally even thought I took my normal dose at the normal time. I am now questioning whether the manufacturer's quality control is up to oar. I sympathize... I wish I had known that this medication was nearly impossible to discontinue.
Im starting tomorrow weening off 150mg after 9 years. I will start 112 for 7 days, then 75 for 7 days finally 37mg for 7 days. I'm terrified, because when I took my meds late I felt like crap! Brain zaps, nauseated, and I stayed on the toilet. I'm asking for prayers plzz,,, Anyone else done these steps??
Hi, Candi! Speaking only from personal experience, my doctor tapered me off over two months from 225mg finally taking doses every other day, every second day, every third day. No discontinuation syndrome at all!
I'd recommend that if you start having symptoms to discuss a slower taper with your doctor.
Also, be aware that when you stop an antidepressant you may have a resurgence of the original symptoms it was prescribed for. This happened to me so I started the Effexor again and have been taking it for another 5 years now... don't think I'll ever want to stop it again!!
Best regards and I hope all goes well for you.
Thank you so much. 13/14 years is a long time to come off such strong meds in three weeks I think!! If it doesn't work after the first week.. Or when I start week two on 75 mg I'm calling y doctor. I can honestly say the medicine does it's job. I don't think it's working for me anymore though. Too many years on it.
"Poop out" is very common when you've been on antidepressants for years. I've been lucky so far!
Stick with your plan and work closely with your doctor. If your depression returns there are lots of options available to you.
G*d bless and good luck.
I went from 150mg to 112.5mg then to 75mg effexor.I hate the way it makes me feel, it gives me unbearable tiredness and dull feeling and has made my life worse for fourteen years.I was told nothing about this evil drug, I was just put on it after the powers that be felt that it would helpe more than Lustral (sertraline) was doing.I didn't find any problem tapering from 150 to 112.5 to 75 but I'm suffering dismal moods and nightmares and worse ocd .I want to go back on sertraline and get off effexor for good but not sure what to do as sertraline may not work after being on effexor?75mg is not effective for me and 150 wsd unbearable drowsiness and worse depression so I'm thinking would 112.5 be possible as a regular dose? If not I will have w switch to Zoloft.I'm terrified of withdrawal after hearing all these accounts of how terrible effexor I'd to come off.
Hello, I was taking effexor xr 225 tablet and wasn't working anymore, so doc switched me to wellbutrin. I weened off the effexor all but an 1/8 of a tablet over the past 4 months. If I don't take that little bit of effexor I get all the side effects. All that I have now are terrible stomachaches, I want to either throw up or go to bathroom and dizziness. Last Thursday, doc had me go off the effexor all together and stay on Wellbutrin and he added 10g of Brintellix.He said my symptoms would go away in 5 days. I've been on it for 4 days and it has not helped one bit and I don't see them stopping by tomorrow. I had to stay home from work today and left a message with the doc. He wants me to stop the Brintellix and putting me on Pristuq tomorrow. He said to take it for 5 days and then cut the pill in half and take the half for another 5 days. We will see. Also, using ginger tea, over the counter nausea meds and they don't help. I'll keep you posted if this helps.
The Brintellix probably was a bad choice for somebody with stomach problems. Are you seeing a Psychiatrist? Can you up your Wellbutrin and add an antidepressant like Viibryd (also partial 5htp1 agonist) or Remeron as it might stop the stomach issues. Wellbutrin and Pristiq sounds like too much nor-epinephrine and a CNS very stimulated, Consider an SSRI, Viibryd, even Abilify with a Wellbutrin increase up to 300mg daily (450mg is too risky IMO)
Howie... The reason I have stomach problems is due to going off the Effexor. I'm currently on 300mg of Wellbutrin, but after ready about Pristuq I'm not sure that will help me ween off the last bit of effexor.No, I am not seeing a psychiatrist, but a counselor. My primary care doc is who changed my meds. Not sure what to do. Thanks for responding so quickly, I really appreciate it.
But Brintellix is known to cause stomach issues such as yours so why giving it to somebody who already has them is beyond me, I understand the withdrawal. What are your primary symptoms of depression? and please consider a psychiatrist, a GP or Therapist isn’t qualified to Rx psych meds
Do you think you will be ok after you get of the Effexor? or do you think you need something along with Wellbutrin?
I'm not sure. I think I will be OK, but won't really know unail I get off the Effexor. We were swapping out the Effexor with Wellbutrin. I've seen a psychiatrist several years ago, but it was decided I only needed to see a Therapist. They couldn't prescribe the meds, so when I felt the meds weren't working I would go to the PCM.
Almost seems like I should take time off of work to go off this medicine with all the stories I'm hearing. Will most of the side effects diminish after 7 days ?
I stopped taking the 150's and it was a nightmare, litterally! It was so bad I had to go on 75mg for 30 days, 32.5 30 days and finally halfing that tab for 30 days, then one every other day for 30 days. Quite an ordeal. Never again!
Thanks! sounds like what I will do next. I will never take an anti depressant again! And now I don't need it... life is better than when I started it.
I read somewhere while researching this drug that it is similar to phencyclidine, or PCP. No wonder, huh?
Swell :(
Yea I had the most awful withdrawal from Zoloft, I would cry then get angry within an hours time and every time I would take a step or turn my head I had brain zaps so bad I thought I was having a TIA or some kind of epileptic episode. It lasted about 10 days peaking around 4-6 then eased up. I hear Effexor can be a life saving Antidepressant but its the hardest to get off of so I honest to god take my hat of to you for being strong enough cuz IDK if I could take something worse than my Zoloft withdrawal. I say make sure you eat enough calories but good food as your body is under a lot of stress it needs proper nutrition and I would supplement with a solid multi vit/min, N.A.C, a B complex, D3, and Melatonin, Astaxanthin is also worth looking into. I know your against medication but Deplin isn't a med really but a Rx food supplement that helps us replenish neurotransmitters which you might need after being on Effexor for so long.
IDK the strengths of Effexor tablets made but you will probably have to go to the IR formula and over 10-12 weeks titrate down to where you end up taking small amounts like 15mg's, or open the XR caps and try and measure (about impossible to do accurately I know) and go a little less each week til you can handle the withdrawal but don't just stop please.
Looks like Lots of brain food needed to go off this crap. Sigh... it's made me worse my anxiety is thru the roof on this medicine. I do so many healthy things to help Myself that I think it's counterproductive to take this medicine. Gym, yoga every day increases serotonin levels. This medicine also deals with serotonin & I think there is a conflict. Going to doctors on the 18th... can't wait to hear what he says.
and for itching try Allegra or generic Fexofenadine, could also mean you need to sweat too
I wish u luck. Please keep us posted on your progress. I want to go off of this too. I was given 37.5 one pill a day script after chemo for anxiety n hot flashes. Been on it a year, now I'm healthy as ever & it's making me so sick. Side effects are kicking in. Migraines, hot flashes are wise, nausea, dizziness &vertigo. I've tried to take every other day to wean off, but I get so sick.
When I was prescribed this drug I read everything about the drug, and didn't want to take it, but I caved. I hope all of us who are on this terrible drug, and want to stop taking, can get off safety.
You can't do every other day yet. I am also weaning and I plan to buy some empty capsules and will start splitting them up. I read that suggestion on this site once.
I had to cut the 37.5 in half for 2 weeks, then 1/4 for 2 weeks, then 1/8 for 2 weeks. I still had side effects when I finally went off, but only for a few days. Good luck!
I have stopped taking this for about a week now and I wish I would've never started taking it. I wish that my doctor would have told me more about the medication or that I would have done more research. I was on 112 mg a day, (75 capsule/37.5 pill). I slowly taper down to nothing just about a week ago. I do have occasional brains zaos/fatigue and feel sick to my stomach. I will Never go on this again. I'm seeing a chiropractor now and started yoga. My hope is to never touch this evil stuff again
Frankie-
Laurie had good advise. Taper slowly if you can. Talk to your doctor. I will add a prayer for you my friend.
I have tried to come off of it numerous times and with working full time and school full time I have not been able to. Talk to your doctor. Maybe you need something to help with the withdrawal symptoms. Prayers. Hope you can stick it out and get through it. Let me know how you were able to get through it.
Thank you for your prayers! I believe prayer will help the most!
Was on 225mg a number of times over the years and weaned myself off as follows Firstly it depends if your capsules contain MINI TABLETS( 12 in 150mg tablet) or Tiny Beads ( app 600 in 150 mg tablet) First week of withdrawal remove 1 mini tablet or approx 50 beads from 150 tab each day Second week 2 mini tabs or 100 beads and so on 225mg ( 1red and 1 pink capsule contain 12 + 6 mini tabs or 900 beads if withdrawing from 225 mg it will 18 weeks No symtoms and worked for me Tapering off lower dose takes shorter Same principle Drop tab weekly until off all Good luck
All you can do without restarting the Effexor and tapering more slowly is to treat the symptoms with over -the-counter meds. Unfortunately, it is going to take some time to adjust to not having the Effexor. You will feel better eventually.
What over the counter meds would help LaurieShay?
My question is also what otc medications are you referring? Thanks 4 any advice!
Really depends on what your symptoms are. As far as the diarrhea, short term use of Immodium will help. The nausea can be addressed using Emetrol or something as simple as peppermint candy or tea. The dizziness and brain fog are going to be difficult to address and will have to run its course.
The brain zaps have been a real problem to me in the past... awful. Thanks for your input.
What are the brain zaps and why are we getting them?
The drug literally changes your brain. I guess changing off of Effexor causes more changes and brain zaps are the brains reaction.
Related topics
effexor, effexor xr, depression, anxiety, vertigo, side effect, prescription, tingling, brain, brain fog
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