Amlodipine was added with Metoprolol and Lisinopril, after about a week of taking all this together he started having very bad joint pain, He had never had these problems before starting this new med. After about 2 weeks he stopped taking the new med and slowly the pain went away. Was it possible that by adding the rx to what he was already taking the combination was working against him,This rx is a little expensive and now we have 3 months supply that will have to be thrown out as he was unable to work while taking this rx Amlodipine thank you for your time