I have never suffered with depression. I've mostly suffered with very bad anxiety with social anxiety. I would say my depression started a few months ago and gradually got worse. Ive started on sertraline 44 days ago (6 weeks) I'm just wondering how long do I have to wait? I have never felt this depressed and horrible before. I was also on Prozac for some amount of time and it was great however it caused me to develop restless leg syndrome and the nightmares were way too vivid so I had to come off them.