Yes! These drugs are NOT compatible:
Using traZODone together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications.
Don't panic, your anxiety may feel worse if you do. Just keep breathing slowly and call your Dr. or go to the Emergency Room. Don't wait around for the Dr. if s/he doesn't call back soon. You may need someone else to drive.