Yes, "4 tablets daily" usually means to take them all at once. The best time to take prednisone is usually in the morning just after breakfast. (Clearer instructions would be "Take 4 tablets as a single dose daily")
As opposed to "1 tablet four times a day" which means exactly as it says (to divide the doses)
- Prednisone Information for Consumers
- Prednisone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Prednisone (detailed)
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