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Pradaxa - How do you handle the severe indigestion & heartburn even taking prevasid?


kriskrisbobis 13 Oct 2011

I also suffered from severe burning stomach pain while on Pradaxa for 30 days post-operatively. As far as I understand, Pradaxa does not increase stomach acid and therefore OTC treatments for heartburn and indigestion do not work. Rather, this is an unpleasant side effect of the medicine itself. I believe it irritates the stomach muscle itself, versus the lining in a number of those who are taking it. I found that eating food BEFORE taking Pradaxa was very important. The larger the meal, the better. Key was, food first, medicine on top and RIGHT after eating. I also found personally that milk seemed to make the burning worse, but I don't know why. Taking Pradaxa alone on an empty stomach was the WORST thing I did. There is a forum on the Pradaxa website itself ( that has a lot of good advice. Hope that helps!

Votes: +0
jkrazi 28 Oct 2017

I'm totally the opposite. In order to remember my second dose I take it at bedtime. Most of the time I'm okay. However when I have a Pre bedtime snack(no judgment please) it happens more than not. Also I find talking it with skim milk helps to swallow it down past my throat and have less problems.

I've never had heartburn, acid regurgitating like this before. I m going to try moving my second dose earlier.

Laying down definitely makes it worse.

Kplu 10 Nov 2017

I experience heartburn very quickly following taking Pradaxa. The manufacturers information states the shell of the capsule contains sodium lauryl sulfate or sodium laureth sulphate. This is soap. I have to avoid this substance in toothpaste as it makes my mouth sore, and I think it is responsible for the heartburn. It is better if I take Pradaxa at the end of a meal, but if it isn't enough food, the heartburn goes on for hours. They warn you not to take anti acids to relieve your heartburn, as it will interfere with the absorption of the drug.

1300vera 1 Jan 2018

I have acid re-flux an I notice when taking Pradaxa at bedtime I have an attack I am going to ask my doctor to change my drug free discount card

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