my L-5 S-1 disk has completely disintegrated (started 11 years ago) my primary Dr. had me on different pain meds most recently Norco (4-5years) until i was hospitalized (sept.3 2012) with liver failure, then diagnosed with autoimmune hepatitis Sept. 11 2012 then was put on Vicoprofen for pain, and Imuran, and Prednisone for the AIH but i just saw the Vicoprofen has a Hepatotoxicity also, my back pain is completely off the charts, and not going away, is there any pain meds NOT hepatotoxic?
What painkillers are safe for people with autoimmune liver disease?
Question posted by passionandpain76 on 28 Feb 2013
Last updated on 19 September 2015
I had Chronic Hep B diagnosed in 1991 until liver transplant in 2011. For pain due to liver/gall bladder related issues my doctor prescribed generic oxycodone and/or generic hydrocodone. These drugs are available without the added tylenol, which, as mentioned in an earlier answer, is the most hepatotoxic ingredient in traditional pain meds. It's coincidental that two years after my transplant, I began to have serious complications, and was diagnosed with autoimmune hepatitis. I too am on Imuran (azathioprine) and prednisone (40 mg/day). Unfortunately, my two year old liver is now cirrhotic, fortunately I am in no pain. Can you recommend any AIH support groups?
Almost any drug passes through the liver to be metabolized. You might be better off taking just plain morphine. You certainly dont want to be on any combo meds that have the opioid in combination with acetaminophen or ibuprofen. It is not so much the opioid that is the problem, it is the acetaminophen and ibuprofen that are hard on the liver.
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