Can you take 1 dose of Ondansetron 1 time only while taking Zoloft? I know they interact if taken regularly but wondering about one time.
Ondansetron and Zoloft question?
Question posted by jshel837528 on 4 hours 12 minutes ago
Last updated on 10 September 2025 (3 hours 52 minutes ago) by WildcatVet
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Answers
Hi, jshel!
You're probably thinking of serotonin syndrome which can be serious in the later stages. Fortunately, it's rare and treatable.
As rare as it is I wouldn't think a one time dosing would be anything to be too concerned about. To be sure you might want to ask your doctor or pharmacist.
Regards, Wildcat
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