I just wanted to know if extremity numbness is normal when reducing prednisone. I am 33 years old and was prescribed a prednisone taper after a bout with ulcerative colitis. I was started out at 40mg with a 5mg taper every 2 weeks, it's been about 4 months now and I just recently started my last taper dose of 5mg and have 8 days left on the medication. The very day I started the 5mg dose I noticed more tiredness and increasing muscle pain, but today I am concerned, the last 2 nights I been waking up in the middle of the night gasping for air, especially when sleeping on my side, and today my left arm feels numb and cold and yet with a burning sensation, but the sensation goes to my right arm and legs at times also, but not nearly as bad as my left arm. My depression has also went up in the last week or so. Weight gain hasn't been a problem because I watched what I ate, low fat etc, but now even one bite of fatty food upsets my stomach. Are these symptoms normal?