... symptoms . I got Monistat 1 thinking it would clear up faster. My vagina was mildly itchy and watery kind of discharge to medium thickness. But after a few hours after inserting the medicine, I wake up in terrible pain. My entire vaginal opening and surrounding area was swollen and red! Not much itch but terrible irritation and soreness!! It is now 4:50 am and it keeps me awake! Did I do something wrong ? Is this normal to be feeling these types of side effects?