I am very scared of side effects and am afraid to start. It has been in cupboard for 2 weeks. 20mg which is lowest dose. I have GAD & panic attacks. Was on it for 4 years until July 2013. Tried to restart in Feb 2014 and doc switched my doses all around for 3 weeks until I quit because of side effects. It worked so well from 2010 to 2013. I should have stayed on but of course thought I didn't need it. No other AD was tolerable for me
Do the majority of people take Cymbalta at night or morning?
Question posted by ljs1281 on 10 June 2014
Last updated on 5 November 2018
24 Answers
Hi! I know several of these posts are older but I wanted to say I’m so relieved to learn others have the exact same hang ups starting new meds! I thought I was being weird or difficult (and maybe I am) but it’s good to know I’m not alone in my concerns. I was prescribed cymbalta to treat pelvic floor pain and the starter dose has been on my counter for 3 days... I’m so nervous taking psych drugs since researchers arent exactly sure how they work to relieve pain. Anyway - I’m very encouraged by the feedback I’m seeing here and I think I’m ready to give it a try! I am uncertain about the time of day to take my dose given my problems with insomnia. Thanks again for sharing your experiences and encouragement with one another. It’s surprisingly comforting and sort of just what I needed!
~ Love and blessings
Hi CherryB. I realize that if I tell you that Cymbalta is a horrible medication you have no reason to believe me; but I still want to let you know that the number of side effects from this drug can be overwhelming. I have been taking it for about 8-10 years now and I finally got to the point that I was able to start tapering off because I couldn’t take it anymore. I hope that you’re planning on taking this medication for the rest of your life; because if not then be ready for the nightmare of coming off it. If you want to check out something about this just google “Eli Lily lawsuits for tapering off Cymbalta”. You might be one of the lucky ones and be ok; but you might not be so lucky. I hope I’m not sounding rude; but I’m so angry that this poison (imo) is still on the market! Take care and best wishes.
Cindy59
Hi all...
I'm taking Cymbalta 60 at night (12 days now)but find i never wake up feeling rested..and also feel anxious and just not great in the mornings too. I might try taking it in the mornings... anyone had a similar experience? I've been chopping and changing meds for a couple of months now... on docs advice. Really hoping for some relief/results. Appreciate any thoughts.. thanks.
Hey I know its been awhile since the last question was posted. I want to make sure those on cymbalta/duloxetine know this issue with this med:
if you plan on stopping for one reason or another, you MUST taper down ie... 1 tab everyday the 1st week, then go to monday-wednesday-friday for 2 weeks, then tuesday and saturday for 2 weeks, then one tablet on sunday x 2 weeks... then stop. Make sure that while you are tapering down you feel ok, you don't have to feel great, but you must feel ok, not thoughts of hurting yourself or anyone else, no deep depression coming over you like a fog. Most people who are on cymbalta are using it for FM pain or depression or chronic pain.
tj, arnp
Taking Cymbalta (60 mgs) at night. I fall asleep but wake up every night after 4 hours! Can't get back to sleep so I am starting today to take the Cymbalta in the morning with my Wellbutrin. I shall see how I sleep tonight. I have a girlfriend on same dosage that takes hers at night and sleeps thru the night! Every body is different so one must weigh the good vs. the bad. I need more than 4 hours of sleep so I'm changing to morning. This is only my 3rd week of Cymbalta. The only thing that has changed in my meds and the fact that I'm not sleeping is the Cymbalta. Will let you all know how it goes!
Alright folks, 4pm here and just took my first dose of 60mg Cymbalta... I'll update.
I just got this medication yesterday, and I took it as soon as I got home which was around 2:30PM, with food. No nausea or stomach upset for me. It took an hour before I realized how much more... quiet my mind seemed to be. It freaked me out a little bit and I had actively to concentrate to think like I normally do. I wasn't straining for basic thought and function, I could still talk and move around just fine, but I did feel a drop in my creativity and couldn't day dream like I used to. (Which would usually lead to intrusive thoughts so I guess this medication is working as intended.) I also sounded very monotone to myself though people I talked to attributed that to me being tired since I still had some emotion and inflection in my speech, but I know it was different than my usual tired monotone.
Despite this, I was able to function okay and by 6PM, I had evened out a happy medium. I was able to day dream again but still be functional. Tired around the edges but not in an exhausting way, (or maybe that's just calm and I forgot what it felt like.) I found it affected my IBS and that kept me up an extra hour and a half last night (from 8:30-10pm on the throne) but I slept like a baby after the fact. No paranoid thoughts, no remembering embarrassments from twenty years ago, no passed guilt, nothing. I've never fallen asleep that easily before but I welcome the transition.
I woke up this morning and immediately had to hit the can, going like a dream. That's unusual because I usually take laxatives for that. I'm attributing it to Cymbalta and decided to take it around lunch time to see if that will work better for me. If not, maybe a morning schedule would be better.
I have to admit, I felt rather off when I woke up. I didn't dream and I'm rather anxious. I made a mistake in a mobile game (that I can't fix or change and will have consequences later down the line,) and I felt like crying over it. I didn't but usually I'd just roll my eyes at such a thing or get mad for like five minutes; not cry or want to cry. I'm also a little bit shaky, like I want to shiver but I'm not cold. I'm not sure if that's because my body's already filtering out the medication and this is withdraw or if it's another kind of reaction. I also felt empty and nauseous after going to the washroom, which was new, but some chocolate milk helped settle that. It is a listed side effect, (the nausea) but I expected it to happen as soon as I took it so be on the watch out. You might experience side effects hours after the fact.
Despite me making it sound terrible, I don't think it's that bad. Overall I'd give it a 6/10. It's not an extreme change, you're not going to lose yourself, things are just going to be quiet for the first couple hours. I was able to day dream again by 4-6PM and had no intrusive thoughts what so ever. (HUZZAH.) Do keep in mind, I'm a complicated case with physical problems that interfere with everything and I've only been on it for one day, so it would be wise to take my account with a grain of salt.
That being said, I'll gladly come back in a week or even on the daily and let you all know how I'm doing. I do recommend trying it and I would say morning doses are a good start for most people, but everyone's body/schedule is different so experiment. You'll be okay, okay? Just don't switch it up every day, changes must be gradual. Be safe and take care!
Okay, it's been seven hours since my second dose and I'm sorry but I must contradict what I said before about not disappearing. You won't but your ability to *feel* anything will. I am numb and soulless and can only sense my emotional distress in this moment. The feeling of emotion isn't there and that's distressing. I have to force inflection and personality into my speech and it is affecting my physical ailments. For a sfw example, I can't feel the need to pee without my bladder nearly bursting. This was a problem yesterday as well but I failed to notice it. Today I did. I'm not convinced this medication is right for me for it does affect not only the brain but the spinal cord and nerves as well, which means pain will be dulled but so will your body's warning systems, such as limbs falling asleep or becoming stiff. These sensations will dull along with your personality and emotional input.
I think the majority of people take Cymbalta in the Morning. That's when I take it. If I take it at night I wind up having nightmares!
My doctor prescribed me cymbalta 60mg a few days ago and I have yet to take it... because like everyone else in this thread I was scared of the side effects. But after reading everyone's responses I just took it.
I'm hoping for the best!
Hi
I was the same but after taking it for 3 weeks I feel so much better physically and emotionally I am now taking 60 my in the morning and 30mg before bed
Iam very scared to start Cymbalta and the Neurontin my Dr just put me on.The horror stories I've read REALLY TERRIFY me..Reading some if the answers to your question is kinda making me think different..I'm still un sure if i'll start it.
I started taking cymbalta two days ago for neuropathic pain and anxiety caused by gabapentin which I'm slowly getting off this is for nerve pain plus bad reactions to epidural injection the doctor has started me on 30mg it is getting rid of anxiety but I feel sick when I take it and it's causing some pain to my nerves I felt a bit sleepy when I took it at noon but only slept for 4 hrs last night I just took 30mg this morning hoping that it might be better for me to take in the morning and sleep at night.
Has anybody else had these effects I have a young child and doctors have put me on different med types I just want this to work
I was just prescribed cymbalta for my neuropathy and anxiety for my MS. I took it two night and literally did not sleep. I felt horrible the next day. I'm scared of new meds with all the problems I'm having. I was told by a friend who is a pharmacy tech that it is safe. I think I will try it in the am after reading all these comments. Fingers crossed!
Hi I am 44 male been on Cymbalta for over a week, and have noticed great changes for me. I talk more to people and I am not shy or depressed as much and believe in time I will get even better. I also just enrolled into Technical College to be a dental asst. I have hope now. I was scared to take it I let it set a couple of days and then decided I am tired of being hateful and fearful. Thank you Cymbalta no side effects so far other than a little tired at times but a nice cup of tea cures it. If you ever come off of it wean off it under your doctors orders so you dont have brain zaps and other withdrawal effects its really that simple. Hope this info helps and please help yourself feel normal again thats why people have took the time to discover and produce these medicines and Cymbalta is not too new so if it was really bad there would be lots of lawsuits not to mention word to mouth. Good Luck! Enjoy your life! =)
Is it still working for U now? I'm getting ready to start it and when woukd u advise me to take it am or pm?
I was just prescribed 40 mg of cymbalta and have been dealing with anxiety and depression idk whether to take it at night or in the am.. It says hypersomnia as a side effect which would be great because I'm not sleeping and wake up multiple times at night with feeling hot and can't go back to sleep easily.. I have anxiety attacks multiple times a day when at work.. But rarely at home.. Thoughts on am or pm?
Hi, I was just put on cymbalta today and was curious about it also. I'm afraid to take meds because I have had so many bad reactions. My doctor reassured me that this is one of the safest medication out there. Not sure if i should take it at night or in the morning.
I’m starting my cymbalta in the morning from reading most of the comments. Can anyone tell me how it’s working for them?
I have been on Cymbalta since 2005 and it has been a miracle drug for me. I have always suffered from bad anxiety and depression and this medication have helped both immensely. I also suffer from a very severe case of fibromyalgia. Cymbals has relieved my pain from this condition 80 to 90 percent depending on the season. Hope this helps people to try this medication. It’s been life changing for me. Good Luck!
I have been on Cymbalta since 2005 and it has been a miracle drug for me. I have always suffered from bad anxiety and depression and this medication have helped both immensely. I also suffer from a very severe case of fibromyalgia. Cymbals has relieved my pain from this condition 80 to 90 percent depending on the season. Hope this helps people to try this medication. It’s been life changing for me. Good Luck!
I have been on Cymbalta 30mg for a couple of years. My Dr also prescribes Wellbutrin to assist with more energy. It seems for as long as I can remember I wake in the mornings feeling exhausted. Either from dreams which leave me feeling like I wasn't even asleep. I take my meds along with Vitamins in the morning after I eat. I use one of those 7 day pill containers to make sure I don't forget. I was wondering if i should switch to taking Cymbalta a night? I remember when first taking it I had insomnia pretty bad. But sometimes, I think we read about side effects and we almost expect them to happen. I read a study done and they even have a name for it when people experience side effects even when given a placebo.
I have tried Cymbalta 30 at 8 PM. I do not feel rested every night. Now switching meds to 8 AM. I do not see much of difference after five days. My cognitive functions are impaired by brain chemical imbalance.
Cymbalta affects two neurotransmitter systems. Serotonin and Dopamine. I think taking it in the morning maybe better B/C the needs for mind's ability to focus on daily tasks.
To further boost Dopamine levels in the day time, I will try to take 500 mg of L-Tyrosine and 25mg of Vitamin B6 with water or juice (recommended by Living Strong)
At night time, I will take 500mg of L-Tryptophan and 25mg vitamin to boost serotonin levels for anxiety and better sleep.
I believe this can be more appealing than bump the Cymbalta from 30 to 60mg without increase SSNRI in my system. What do you all think?.
please always check with your doctor before adding even OTC or vitamins/supplements as there can be complications. Self-medicating is probably the one thing we all try but don't realize the impact of. Good luck.
Actually this is a old comment but Cymbalta increases Norepinephrine AN Serotonin not Dopamine. Thats Wellbutrin.
Related topics
cymbalta, depression, anxiety, panic disorder, generalized anxiety disorder, side effect, dosage
Further information
- Cymbalta uses and safety info
- Cymbalta prescribing info & package insert (for Health Professionals)
- Side effects of Cymbalta (detailed)
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