I am very scared of side effects and am afraid to start. It has been in cupboard for 2 weeks. 20mg which is lowest dose. I have GAD & panic attacks. Was on it for 4 years until july 2013. Tried to restart in Feb 2014 and doc switched my doses all around for 3 weeks until I quit bc of side effects. It worked so well from 2010 to 2013. I should have stayed on but of course thought I didn't need it. No other AD was tolerable for me
ljs PLEASE you know how bad you feel and it worked at one time it is going to do no good in the cupboard there is no reason to suffer with these problems now days and yes you may have side effects when you first start it again..But the subside after continued use..Please start your med..this is a very good one for what you say and you are starting with the lowest dose... I have been on medications for 20 years and finally can do just about anything now with cymbalta it is a very effective medicaton and replaces serotinin that your brain makes this suppliments it..Anyway Please if you work try and start this on your first day off so you don't have to worry about if it makes you very tired or what ever... you know it does nogood in the cupboard you must start it asap..Now for your queston about when it works different for some people so start it in the morning because sometimes it can make it so its hard to sleep for some people so i would say take in in the am...
you can always change it later if it makes you tired change it to night time..it has no special time so please go with the flow dear and know thereare lots of us here and we do care..you are not helping yourself by not taking it andiam not trying to be mean.if you have more questions pleasepost it..we care.Chuck1957 medically retired pharmacy technician Cpht...
ljs Chuck again here is some infor i copied and paste..that may help you remember never open and sprinkle capsule this is timed release swallow whole as it says here but this is some of the most importints stuff to remember okay here is the copy and past plese start YOUR MEDS TODAY.OR CHECK BACK WITH DOCTOR chuck1957************Advise patient to take prescribed dose without regard to meals, but to take with food if stomach upset occurs.
Advise patient to swallow capsule whole, and not to crush or chew the capsule. Caution patient not to open capsule and sprinkle contents on food or mix with liquids.
Inform patient that it may take 1 to 4 wk to note improvement in symptoms and to continue with prescribed therapy once improvement has been noted.
Instruct patient to notify health care provider if symptoms do not appear to be getting better or are getting worse, or if bothersome adverse reactions (eg, changes in sexual function, diarrhea, drowsiness, headache, insomnia, nausea, nervousness, unusual sweating) occur.
Chuck, thanks for the information. This has been going on since march. I don't have depression. ..just bad anxiety and health/social anxiety. Over reactive fight or flight response. My doc thinks bc anxiety was so high in February when I tried to restart cymbalta I really didn't have side effects but rather anxiety attacks of that makes any sense. Also she said her mistake was trying to up dose too fast then kept dropping it and upping it until finally after 3 weeks I quit taking. I'd love to go back on it bc from 2010 to 2014 it worked for anxiety at 60mg. Do you think 20mg is going to cause bad side effects? I also take a very low dose blood pressure pill. Thanks
I tried taking it both in the morning and switching to night time. I found it was better to take at night for me. I have the same problem as you and starting medication scares me. I know its weird. We need the help, we want the help but then we are afraid of the help. I think it took about a week for me to work up the courage to take it. Having been on Cymbalta for a long time, I can say that 20 mgs. is a good low dose to start. Just remember that you have taken it before and you didn't die or go crazy. It will take some time to work its way back up to where you feel good like you did awhile back. Just be patient with yourself.
Remember to take with food. Do not crush or open the tab. Just swallow it with a glass of water after you have eaten some food. If you feel like you are too drowsy and you are taking it in the morning, try taking the dose at night. If you find you cannot sleep and you took it at night, try taking it in the morning. Maybe start on a weekend when someone can be with you to help ease the anxiety of starting it again.
Cymbalta ( Duloxetine ) is a serotonin and norepinephrine reuptake inhibitor. This means that in a week to four weeks the brain levels of serotonin and norepinephrine are increasing. One needs to give this two or more months to have the best effect. ( if effective ) Serotonin tends to " calm" the brain. Norepinephrine tends to stimulate and focus the brain. Effexor,Prestiq, Cymbalta, and a recent " arrival" Fetzima are SNRI's. Prozac , Paxil, Zoloft, Celexa, Lexapro, and others, including the " new" arrival Brintellix are SSRI's ( increase Serotonin reuptake. Wellbutrin regular release and extended release increase Norepinephrine and some Dopamine ( reuptake inhibition )
This medication tends to excite and " motivate " the brain. This medication is helpful in treating Seasonal Affective Disorder, reducing smoking, and has some effect in treating ADHD. Increasing Serotonin in some individuals may result in a sense of indifference, or decreased motivation, or decrease in " passion" This decrease in emotional experience needs to be distinguished from depression. The SSRI and the SNRI medications may result in sexual side effects. Wellbutrin does not have sexual side effects. Many medications including OTC's are metabolized in the liver. Some individuals have a large amount of these enzymes, some an intermediate amount, an others a small amount. ( CPY 450 and subtypes ) Thus, one person may be a slow metabolizer, a small amount of enzyme ( a little bit goes a long way ) another person may be a fast metabolizer , a large amount of enzyme ( a high dose is needed to have an effect ) Then some people are in between.
Thus, ( given other variables such as drug-drug interactions ) different doses may be required to obtain the desired clinical effect. Bear in mind that generic medications may have a different " filler" and a dose range of 80 to 120 % of the branded medication. I have seen a number of patients do poorly on generic Cymbalta. Do not stop these medications abruptly. One may experience discontinuation symptoms. A gradual weaning is in order. Should you have any questions about your medications or possible drug-drug interaction ask your doctor or pharmacist. I might add, genetic testing of liver enzyme profiles are available. This is obtained with a mouth swab. Of course, there is a cost. I hope some of this lengthy comment is helpful.
I feel your pain; and was so happy to know there was someone out there EXACTLY like me. Hope you get this note; I'm interested in how you're doing. I was taking Celexa for 7-8 yrs and decided I no longer needed it because I felt I didn't have fibromyalgia any longer. I phased myself off of it correctly, but I guess my body was so used to it after that long, that when I was off of it for a year, I started having ALL KINDS OF PROBLEMS. It didn't work to go back on it either. Now a different dr wants to start me on Cymbalta and I have the same anxiety about starting something with potential side effects. Just glad to know there's someone else out there like me with the reservations about these meds.
Just started Cymbalta today; remaining hopefully that it works. I've been on meds 17yrs now. I seem to fall in the criteria so here's hoping. I've always taken my meds at HS so I started Cymbalta with the same regime. I've had a huge break in my mental health.. I feel awful but im anticipating within a few weeks I'll start feeling more like me again
I have tried Cymbalta 30 at 8 PM. I do not feel rested every night. Now switching meds to 8 AM. I do not see much of difference after five days. My cognitive functions are impaired by brain chemical imbalance.
Cymbalta affects two neurotransmitter systems. Serotonin and Dopamine. I think taking it in the morning maybe better B/C the needs for mind's ability to focus on daily tasks.
To further boost Dopamine levels in the day time, I will try to take 500 mg of L-Tyrosine and 25mg of Vitamin B6 with water or juice (recommended by Living Strong)
At night time, I will take 500mg of L-Tryptophan and 25mg vitamin to boost serotonin levels for anxiety and better sleep.
I believe this can be more appealing than bump the Cymbalta from 30 to 60mg without increase SSNRI in my system. What do you all think?.
I have been on Cymbalta 30mg for a couple of years. My Dr also prescribes Wellbutrin to assist with more energy. It seems for as long as I can remember I wake in the mornings feeling exhausted. Either from dreams which leave me feeling like I wasn't even asleep. I take my meds along with Vitamins in the morning after I eat. I use one of those 7 day pill containers to make sure I don't forget. I was wondering if i should switch to taking Cymbalta a night? I remember when first taking it I had insomnia pretty bad. But sometimes, I think we read about side effects and we almost expect them to happen. I read a study done and they even have a name for it when people experience side effects even when given a placebo.
I was just prescribed 40 mg of cymbalta and have been dealing with anxiety and depression idk whether to take it at night or in the am.. It says hypersomnia as a side effect which would be great because I'm not sleeping and wake up multiple times at night with feeling hot and can't go back to sleep easily.. I have anxiety attacks multiple times a day when at work.. But rarely at home.. Thoughts on am or pm?
Hi I am 44 male been on Cymbalta for over a week, and have noticed great changes for me. I talk more to people and I am not shy or depressed as much and believe in time I will get even better. I also just enrolled into Technical College to be a dental asst. I have hope now. I was scared to take it I let it set a couple of days and then decided I am tired of being hateful and fearful. Thank you Cymbalta no side effects so far other than a little tired at times but a nice cup of tea cures it. If you ever come off of it wean off it under your doctors orders so you dont have brain zaps and other withdrawal effects its really that simple. Hope this info helps and please help yourself feel normal again thats why people have took the time to discover and produce these medicines and Cymbalta is not too new so if it was really bad there would be lots of lawsuits not to mention word to mouth. Good Luck! Enjoy your life! =)
I was just prescribed cymbalta for my neuropathy and anxiety for my MS. I took it two night and literally did not sleep. I felt horrible the next day. I'm scared of new meds with all the problems I'm having. I was told by a friend who is a pharmacy tech that it is safe. I think I will try it in the am after reading all these comments. Fingers crossed!
I started taking cymbalta two days ago for neuropathic pain and anxiety caused by gabapentin which I'm slowly getting off this is for nerve pain plus bad reactions to epidural injection the doctor has started me on 30mg it is getting rid of anxiety but I feel sick when I take it and it's causing some pain to my nerves I felt a bit sleepy when I took it at noon but only slept for 4 hrs last night I just took 30mg this morning hoping that it might be better for me to take in the morning and sleep at night.
Has anybody else had these effects I have a young child and doctors have put me on different med types I just want this to work
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 22 Apr 2012 • 3 answers
Posted 14 Jul 2014 • 2 answers
Posted 9 Dec 2014 • 1 answer
Posted 22 May 2016 • 1 answer
Posted 16 Dec 2016 • 1 answer