Skip to main content

I just started zoloft and Im feeling really nauseous how long do these side affects last?

12 Answers

Njatich 4 Feb 2022

Hi. Sorry you’re feeling like that. I too went through this. It does pass but it may take some time. Everyone is different. Mine lasted 3 months. I’ve been taking 50mg everyday and I’ve notice a huge difference. My anxiety level has come down a lot. I wanted to quit so many times but I’m glad I stuck it out. In the long run it was worth it. Try not to give up. Try taking it with food. It helped me. Good luck on your journey and don’t give up. You’re not alone.

Votes: +0
kimmychoo 4 Feb 2022

i have been taking Zoloft 50mgs for about a week now. I started with breaking them in half; i took my first whole one today and feel so nauseous!!!

Votes: +0
WildcatVet 3 July 2019

Hello! This is a common side effect when starting Zoloft and it usually resolves rather quickly getting better every day. Ask your doctor or pharmacist about OTC remedies such as Emetrol, Dramamine-N, and meclizine.
"Very common (10% or more of users): Nausea (up to 18.3%)"
"Side effects have been reported to be generally mild and transient. They are most common during the first 2 weeks of treatment and decrease in intensity and frequency with continued treatment. They generally do not lead to treatment cessation."
You can also try eating frequent small meals like soda crackers, ginger ale, yogurt, etc.
Best regards and I hope you feel better quickly. Zoloft is an excellent choice for depression/anxiety!

Votes: +0
WildcatVet 3 July 2019

BTW, cannabis is a depressant drug. Not a good idea to pair it with an antidepressant as it can interfere with the efficacy of your Zoloft.

breakingbailey 3 July 2019

It wont work for everyone but the nausea subsided for me completely after 2 days when I smoked a joint of cannabis when the nausea kicks in. Everyone has different preferences but this absolutely works. Maybe eating it would help too but not tried it.

Votes: +0
babesgirl96 19 May 2017

i just started taking 50 mg of zoloft yesterday and im tired all day cant sleep at night and have nausea and bad pains in my stomach. im not sure what i can and cant take with this bc i take prazosin for nightmares also. so if someone could let me know what works that would be very helpful.

Votes: +0
Bg2112j 4 Oct 2016

I started Zoloft 3 weeks ago on 12.5 mg for 4 days and increased to 25mg for a week, then 37.5 for 4 days and I just started 50mgs last night. With every increase I have had the nausea and felt tired during the day and yawned a lot but all of this side effects subside right about when I'm ready to increase. The nausea is worse with the 50mgs so far but I don't think it will take long to subside. For the insomnia I take hydroxyzine which was prescribed to me for panic attacks but I have found that it works well for the restless legs and sleeplessness and I wake up only slightly drowsy.

Votes: +0
luminousbeam 17 Nov 2012

You might ask your doctor (regular doc if pdoc cannot) for Zofran to go along with your Zoloft. Only take the Zofran when you really need them and they should help your nausea.

Votes: +0
02jeepgirl 4 Dec 2011

I just started taking Zoloft almost a week ago. I cannot sleep, when I close my eyes and lay down I feel like the room is moving. I feel nauseous and rapid heart beat. I wish I could tell you it will go away, I am new to it. But I really dont like it. I am thinking of calling the doctor Monday.

Votes: +0
kimmychoo 4 Feb 2022

that might also be your anxiety

AngieGutterman 19 June 2011

I wish I could answer that. I have been on it for one week and been terribly nauseous and suffer from sleeplessness as well. I was originally on zoloft about 5 years ago and it did very well for me and I do not remember suffering any side effects. I actually thought that I no longer needed Zoloft and went off for several months. Now, I am back and wish I never would have quit. If I find something that works for me, I will let you know. Good Luck!

Votes: +0
sweetie pie 17 June 2011

Hi carisab!, I remember having some mild nausea when I first started Zoloft some time ago, but it only lasted a few days. You may want to contact your doctor if the symptoms do not go away. You may either need something for your nausea( phenergan) or possibly have your medication changed. The nausea should not last more than a few days. Nobody wants to suffer with nausea that long and they do not have too! So please contact your doctor so that youi can get some relief. I am so sorry that you are going through this. I wish you the best. Let us know how you are doing. Sweetie Pie

Votes: +0
LaurieShay 15 June 2011

Yep as Pledge shared the nausea is a common side effect and will get better with time. It may take a couple weeks though. Try to take the Zoloft with a little food and that may help the nausea. With continued use the nausea will subside, so hang in there!!


Votes: +1
Inactive 15 June 2011

Hello carisab. I was on zoloft, and yes was nauseous. It left me after several weeks. My dose was around 250mg. The nausea is a normal side effect. Try taking an over the counter anti-nausea medication, that might wishes to you.

Votes: +0 free discount card

Related topics


Further information

Similar questions

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.