My doctor gave me Latuda to try, but I told him I am 10 weeks pregnant Is that goint to affect the baby? Also, I ask my doctor if Latuda have any side affects. Before I take this drug I would like to get a clear answer in what I am taking and if it's safe for my baby. Please help.
As far as using Latuda while pregnant, the literature say the following:
Lurasidone was not teratogenic in rats and rabbits. There are no adequate and well-controlled studies of Latuda in pregnant women.
No teratogenic effects were seen in studies in which pregnant rats and rabbits were given lurasidone during the period of organogenesis at doses up to 25 and 50 mg/kg/day, respectively. These doses are 3 and 12 times, in rats and rabbits respectively, the maximum recommended human dose (MRHD) of 80 mg/day based on body surface area.
No adverse developmental effects were seen in a study in which pregnant rats were given lurasidone during the period of organogenesis and continuing through weaning at doses up to 10 mg/kg/day; this dose is approximately equal to the MRHD based on body surface area.
Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery. There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress and feeding disorder in these neonates. These complications have varied in severity; while in some cases symptoms have been self-limited, in other cases neonates have required intensive care unit support and prolonged hospitalization.
Latuda should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
The common side effects of Latuda include the following: Agitation; anxiety; dizziness; drowsiness; fatigue; lightheadedness; nausea; restlessness; stomach upset; vomiting; weight gain.
If any of these side effects become bothersome, please contact the doctor right away.
I do not think you should be taking any psychtropic drugs while you are pregnant and also when you have your baby. They can cause horrendous side effects including brain damage. Biopolar cannot be proven scientifically by any form of medical or biological test and your behaviour and present feelings could probably be caused by the fact that you are pregnant and your hormones are all over the place and your body is going through huge changes.
Embrace this and go with it. Dont try to drug what is natural. I do not accept biopolar as being a valid and genuine disorder. Every person is different and we all react to stress in different ways. Having ups and downs in life is natural.
Not everything is a mental illness ... Put your real health and your baby first and look forward to your bundle of joy and good luck.
According to the product insert paper (the long description which comes with the drug) their rat and rabbit studies resulted in no birth defects. However-they go on to say that its use during the 3rd trimester of pregnancy has resulted in infants having a number of different problems, some of which "have required intensive care unit support and prolonged hospitalization."
In short, the product insert paper says "Latuda should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus"
I hope that this helps,
I don't know the specific answer to this, but I'm taking it that the other posters are correct in saying that the studies may only have been conducted on rats and rabbits, and that the results are inconclusive as to it's affects on humans.
I never was in your position, what with having to make a value judgment about either taking a bipolar drug and taking a risk with my baby's development, or not taking anything for the well-being of my baby. I had four children, and Thank God I was never in that bind. However, with my first, I got a horrible infection courtesy of an incoming impacted wisdom tooth, and the pain was unbearable. I went around for nearly three months in excruciating pain... couldn't sleep at night, nor was prepared to go for surgery. The doctor COULD have given me an anti-biotic specifically for that kind of infection, but he said that it had only ever been tested on rats. So my decision was to foregoe on the drug, as I was unwilling to take that gamble.
This is quite different, as we are talking about bipolar now. I disagree totally with stopdrugging that bipolar doesn't exist... I don't think that he/she ever experienced a psychosis... otherwise she'd come to a very rude awakening that it is far from a speculative, intangible thing. Madness/mania/bipolar DOES exist..and it's a little bit more than an alternative state of mind, or some people's reactions to stress.
My prayers are with you whatever you decide to do. I probably know what direction I'd lean in on this, but only you can make a choice decision on it. God Bless you and your baby.
Considering there is always a risk for any rx meds you take while pregnant, the very best advise I think would be to discuss this with your OB and get his opinion first. If your comfortable with his opinion, go with it. If not, do the research in depth. You have to feel 100% good about it either way. I was one of those pregnant moms that wouldn't even take aspirin and drank milk for 9 months! Still, 1 son has ADHD, and my other 2 children sometimes deal with a mild depression. So... you just have to do what's best for you, and pray for a happy and healthy baby. Best of luck ^_^
I am about 4 weeks from delivery and have been taking latuda for the durration of my pregnancy. So far so good, everything is fine, i talked to the Dr. about the side effects it could have once the baby is born and she said that the most common side effect in infants is the possibility of tremors. She informed me that it should not be taken while breast feeding and for that reason alone i have recently quit taking it. It is highly reccomended that you take your prenatals while taking this as it will decrease the risk of birth defects, but judging by my last ultra sound a few days ago, there are no physical visible defects. I hope this information helps.
I am also pregnant and have bipolar. Very manic and when it's bad I crash into real crappy depression. When I found out I was pregnant I was about 8 weeks and my primary dr took me off ALL My meds just like that. After being on800 mg of Seroquel for the last 7 years just about.
I got an apt with my baby dr.( He is a high risk pregnancy dr) and he said that I could go back on my meds if me taking them out weighted the bad... He wanted to wait till the 2 and trimester if we could. Well I decided I needed to go back on the Seroquel after being completely off for the last 2 months. Well I was very hesitant because most phyc. Meds are class c witch means they haven't done enough research in pregnancy to know weather or not it cause's any birth defects.. but... I need to be ok to carry this baby and take care of my other4 kids.my 2 girls and my fiancé 2 bots we have part time. So if u need to be on meds... Take them now before u crash or the symptoms become worse cause then the medication takes twice as long to work and your still driving yourself nuts with the racing thoughts and the hyperemesis and the insomnia( witch I have now).
Good luck your baby will be ok Hun as long as mommy is ok. Especially if it's a class b that's better than c.:)
I am 18 weeks pregnant now and thank goodness I started back on my meds cause idk how o would feel if I didn't with my hormones already not helping..lol
Regarding use of Latuda during pregnancy, I would like to offer you a STRONG WARNING in regards to using Latuda while pregnant. I also have bipolar and was taking Latuda while I was pregnant several years ago, as it was considered to be among a class of 'safer' meds during pregnancy (category B: in animal reproduction studies, no apparent risk to fetus). I did not detect anything alarming with the pregnancy for about the first six months, although many people constantly commented on how small my belly was at this time. This being my first pregnancy, I did not know exactly what to expect. Around this six-month mark, however, I began to notice that I could not feel the baby moving at all for several days in a row.
I then went to the hospital where they told me that there was virtually no fluid in my placenta. A few short minutes later, I was whisked away for an emergency C-section. Despite some difficulty at first, he was born alive. He continued to survive throughout the span of the next six days. Doctors tried to relay to me exhaustive lists of a dozen complications during this time. Sadly, my husband and I lost him upon the sixth day.
I was far too traumatized at the time to analyze the symptoms that led to his failure to thrive. My mom, however, (who is a nurse) took it upon herself to take his medical record, along with information gleaned from conversations with his doctors to identify symptoms of our son's illness that were listed among the side effects of my then-medications (lithium and Latuda). A review of lithium did not turn out anything substantial; however, despite having been reported as one of the safer antipsychotics, the list of side effects shared between my son and myself (while having been pregnant, and at no other time) were numerous: loosely a dozen, and roughly 6-8 very clearly identifiable ones. (I am not able to recall them specifically, as to this day I believe I have still blocked it out.) To me this indicated a causal relationship between my use of the drug Latuda and the loss of our six-day old child. While I may never be able to prove this (I declined an autopsy for personal reasons), it is a belief that I hold to my very core to this very day.
HOWEVER, Latuda may well benefit your mental health, including inhibiting relapse, which can also be critical to the safety of mom and baby. I would encourage a thoughtful review of your medication options, particularly by seeking it out from a psychiatrist--all the better if he/she has a focus on pre- and postnatal care.
Your health comes first. You will be the healthiest and the safest with the medication(s) to which you respond the best.
May you and your baby be well. God bless.
- Latuda Information for Consumers
- Latuda Information for Healthcare Professionals (includes dosage details)
- Side Effects of Latuda (detailed)
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