I got Synvisc One injection from Dr. on April 21, 2011. He gave it like an ordinary injection in the knee and said Synvisc One will go in the knee joint on its own. I feel injection is not in the joint, I have severe unbearable pain in the knee, very stiff burning pain, cannot walk and find difficult to drive . At times I feel like throwing up. After I complained to Dr. O\Brian he told me that he cannot do anything for me and go to family Dr.. Family doctor knows little about this injection I don’t know what to do. I don’t know what kind of side effects this material has and how long this will go on. Please help. Called Genzyme many time. No help.