Hi, Had to take 250 mg of Depakine (Depakene/depakote) for my mood (subscribed from my housedoctor. Took it 11 days. Quit on monday because of severe side effects (heavy legs, sweating, heart palpitations, etcetera). It's funny that the heart palpitations are not mentioned in the leaflet over here (Europe) but on the internet I can find information that they ARE a side effect but less common. I underwent an ablation in october last year. Everything was fine but that stopped when taking this medication. Anyone can relate?