Why can't I have grapefruit while taking seroquel?
- 24 Oct 2013 by Bridie Jo Dennison
- 24 October 2013
- seroquel, schizophrenia, grapefruit
I take 100mg of Seroquel twice a day, for schizophrenia.
It has to do with the metabolism of Seroquel. Seroquel is metabolized in your liver by CYP3a4 enzymes. Grapefruit is a protent inhibitor of these enzymes. Taking the two together causes seroquel to accumulate and leads to potential side-effects.
Hi, Bridie! Just FYI, other fruit juices ~ orange, apple, grape, etc. ~ will not cause an interaction.
Best wishes, WCV
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