Evenity - How many people reported as having side affects or heart attack or stroke?
Question posted by ladyslippert on 14 Nov 2023
Last updated on 15 November 2023 by masso
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Answers
Cardiovascular
During clinical trials, this drug increased the risk of cardiovascular death, heart attack and stroke in the compared with alendronate, but not compared with placebo; myocardial infarction occurred in 16 (0.8%) women receiving this drug compared to 5 (0.2%) receiving alendronate and stroke in 13 (0.5%) and 7 (0.3%) patients receiving this drug and alendronate, respectively. These events occurred in women with and without a history of MI or stroke. Cardiovascular death occurred in 17 (0.8%) and 12 (0.6%) of patients receiving this drug and alendronate, respectively. Positively adjudicated MACE (major adverse cardiac events; composite endpoint of cardiovascular death, nonfatal MI and nonfatal stroke) was significantly different at 41 (2%) and 22 (1.1%) in patients receiving this drug and alendronate respectively.
In the placebo-controlled trial, the number of women with positively adjudicated MACE was not significantly different with both groups reporting 0.8%.
Common (1% to 10%): Peripheral edema
Uncommon (0.1% to 1%): Myocardial infarction, myocardial death
don't know this drug; sorry.
Related topics
heart attack, osteoporosis, ischemic stroke, side effect, heart, evenity
Further information
- Evenity uses and safety info
- Evenity prescribing info & package insert (for Health Professionals)
- Side effects of Evenity (detailed)
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