I currently take 60 mg Cymbalta and need to switch to Zoloft (ultimately to 200 mg). Do I have to taper off Cymbalta and slowly add Zoloft? How does this work? Anyone switched before? Thanks a lot.
Change from Cymbalta to Zoloft -- what's the process?
Question posted by hankmac on 27 May 2013
Last updated on 16 May 2018 by Outlook8
I was on 60mg of cymbalta for 2 1/2 years, I have recently weaned off it. I reduced to 30mg for 28 days, no worries. Then 1 day nothing, until I started 25mg of zoloft. It was horrible for 3 days, head spins, tears. I rang my gp, he immediately upped my dosage to 50mg, but he checked if I had nausea first. No, now feel much than 4 days ago!
I once missed taking duloxotine for 3 days and it made me feel like death! I was paranoid, dizzy, felt sick and unsafe. I am slowly coming off this medication as it makes me feel low and tired all the time. This is not the medication for me!
Thanks everyone for your very helpful answers. My internist told me I could make the switch pretty quickly but I was concerned about doing it so fast. I will definitely go slow and get the Cymbalta out of my system before introducing Zoloft. I was on Cymbalta once before and it was terrible getting off it. I don't think some doctors really realize how difficult and dangerous these drugs and their interactions can be. Thanks again!!!
Tapering Cymbalta is not super easy for many. Go very slow and very gradually decrease your Cymbalta dose each week. Some people take months to get off of Cymbalta.
You have to be tapered off cymbalta totally before taking Zoloft. My doctor said people have very bad side effects if you take both drugs together.
Your prescribing physician should be tapering you off the Cymbalta and starting the Zoloft.
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