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Can Nyquil or Benadryl cause a false positive for methadone?


suzanne66 25 May 2011

Yes, the dextromethorphan in Nyquil and the diphenhydramine in Benadryl could both give false positives for Methadone

Votes: +0
Inactive 25 May 2011

Hey Mmc,

The following lists some of the common medicine/conditions that can cause a false positive for opiates:

You will see that Nyquil can cause a false positive for opiates as well as amphetamines.

Hope this helps,


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benadryl, nyquil, methadone, drug test

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