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Bydureon - Has anyone had lumps at the injection site? I inject near my belly button?
Question posted by kaaos on 1 July 2012
Last updated on 22 September 2021 by Ron 3578
24 Answers
I have been on Bydureon BCISE for about 5 years. I also get bumps weekly but inject on different abdomen sides each week. My only complaint is sometimes the pen will not inject the medicine and then discharges when you remove it from your body. This stuff is way too expensive to be wasted. Overall satisfied with drug performance. Went on it after a lactic acidosis reaction to Metformin.
I have been on bydureon for well over 6 months. Never had an itching problem til last weeks injection, which is also the injection that hurt and bleed like crazy so i must've hit something. Yes lumps and more lumps, they dont bother me they are a nuisance. The bumps allegedly go away in 4 weeks but also remember thats for each bump. So if you have 5 bumps that would be 4 weeks from each injection. This medicine is my first besides metformin as well and has tremendously helped me. I have went from an A1C of 9.8 to a 6.1 in a month, lost some weight and my blood sugars now remain in the low 100-115 vs. My old 290-300. I have no switched to my thigh this week just to see if the bumps go away as they claim. Good luck y'all
I've taken the injections 6 time and have large bumps on my stomach and they hurt and itch. My doctor failed to tell me about this, he stated you can get dizzy but no bumps which hurt when sleeping.
When I Used it on my upper leg got several lumps. Switched to my side no lumps. Did have injection site itch several times but no longer . Dr did not seemed concerned with lumps
I have been taking these shots for a few months now. I have a bump for each injection. I have noticed that some of the bumps are slowly going away. I also have noticed more itching at the injection site now but didn't notice it as much (when I first started giving myself the shots).
My numbers began to increase to 160-170 in the morning after fasting and in the 220-250 range after dinner so around Thanksgiving 2017 my doc put me on Trulicity. That worked great in addition to my daily Metformin, but due to the excessive cost we decided to give Bydureon a shot (no pun intended).
The first weeks were fine. I injected a few inches to the left of my belly button. A few days after about my 3rd weekly injection (left side), I noticed a bit of stinging at the injection site. If I ran my finger over it or pressed it, I'd say it felt like a bee sting. Not excruciating, but not pleasant.
The next few weeks I moved over to the right side, staying in an area about three to four inches from my belly button. I have not had the bee sting issue, but I got the lumps. I'd say these are about 1/2 inch wide. The good news is the first one went away, so I assume the others will too. My numbers are slowly coming down (130-150 in the morning, 200-210 after meals) but I need to eat better and exercise more so I know I can improve on that.
My A1C was 7.1 (Jan 16) then 6.6 (Jan 2017) the back up to 7.6 (Nov 2017) and back down to 7.3 (Jan 2018) so I'm getting it back down.
Hope this helps!
My insurance company will not cover Victoza until I can document 2 other alternative drugs do not meet my needs. I tried Trulicity but saw no improvement in my A1C's or weight. I'm now on Bydureon - I have taken 4 doses so far. My first injection site is a large, bruised, itchy lump on my thigh. The next three sites have been in my hip, my belly, and my upper arm. All have the same large, itchy bruise. I don't know if this is going to improve my numbers but the process of "mixing" this pen along with the aftereffects of the injection make me realize I would go back to Trulicity if I can't go back to Victoza. (I was on Victoza for almost 2 years with great success).
When I picked up Bydureon, the instructions from the pharmacist included watching YouTube videos to understand the mixing process. Really??? That meant from the very beginning, this drug seems difficult to use. I take the pen out of the refrigerator (I started with the recommended 15 minutes but now do it several hours ahead of time) and know it will take me 10-15 minutes to get the pen mixed. I have arthritis in my hands -- "tapping" the pen to get it mixed is very painful. And the additional insult is the intense itching this drug has created. I can almost handle the lumps and bruising, but the itching is driving me crazy!!!
Any suggestions for other medications if I can't get the insurance company to approve Victoza again?
I had the lumps too! They started as red itchy lumps warm to the touch. After awhile the redness went away and left me with lumps allover my belly. My doctor didn't think there was anything wrong with having lumps and now I don't see that doctor anymore! My friend sags it was probably an allergic reaction.
Developed a big hard belly lump at in injection 4. Then I quit taking Bydurion as it did not seem to be doing any good anyway, and that horse needle was the pits. Victoza is much better at curbing appetite and permitting multi-day fasting which is the real secret long term "cure" for T2. Three weeks on I still have the hard lump. Hoping it will dissipate soon.
I have been on bydureon for about 12 weeks I only have lumps in my thighs. Unfortunately I get better results in my thighs. I was going to contact my dr and see what she says. I'll update
10 weeks, nodules still present . Was told the nodules were supposed to be the size of a bb. These are 2cm. Itch and have a bruise where the nodules are.
Yes , lumps and itchy at times. Now experiencing nausia and weakness.
I started on Bydureon 5 weeks ago. After 3 injections I noticed the lumps. I completely freaked out! I read a suggestion about using an ice pack for 15 minutes afterwards. That worked well - only got a small lump that time. I sure hope these go away. Very disconcerting to read that some injection site reactions may require SURGERY??? (I'll get Lipo and a tummy tuck while I'm at it!
3 weeks using this injection only noticed the lumps after 3rd injection that became itchy after going swimming I thought I'd been bittern then realised these were the 3 sites I'd injected so I googled it to see it's quite a common side effect due to administer a dose tomorrow and I'm unsure if I want to do it as the irritation is unbearable plus these lumps are quite large and hard could it be due to not mixing it well ?
My second shot, I had a huge lump in my leg (which lasted several months). Half an hour later I started vomiting. Three days I couldn't hold anything down and all I could do was sleep. I did lose 17 lb. I have not taken it since.
Related topics
Further information
- Bydureon uses and safety info
- Bydureon prescribing info & package insert (for Health Professionals)
- Side effects of Bydureon (detailed)
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